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» Authors » Agnes C Cheruiyot

Agnes C Cheruiyot

Explore the profile of Agnes C Cheruiyot including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 17
Citations 150
Followers 0
Related Specialties
Science
General Medicine
Pharmacology
Top 10 Co-Authors
Hoseah M Akala
Ben Andagalu
Dennis W Juma
Edwin Kamau
Edwin W Mwakio
Redemptah Yeda
Benjamin H Opot
Redemptah A Yeda
Jelagat Cheruiyot
Bernhards R Ogutu
Published In
Antimicrob Agents Chemother
PLoS One
Malar J
Am J Trop Med Hyg
Sci Rep
Affiliations
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Recent Articles
11.
Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels
Cheruiyot A, Auschwitz J, Lee P, Yeda R, Okello C, Leed S, et al.
Antimicrob Agents Chemother . 2016 Feb; 60(4):2417-24. PMID: 26856829
The malaria SYBR green assay, which is used to profilein vitrodrug susceptibility ofPlasmodium falciparum, is a reliable drug screening and surveillance tool. Malaria field surveillance efforts provide isolates with various...
12.
The Genotypic and Phenotypic Stability of Plasmodium falciparum Field Isolates in Continuous In Vitro Culture
Yeda R, Ingasia L, Cheruiyot A, Okudo C, Chebon L, Cheruiyot J, et al.
PLoS One . 2016 Jan; 11(1):e0143565. PMID: 26751382
The Plasmodium falciparum in vitro culture system is critical for genotypic and phenotypic analyses of the parasites. For genotypic analysis, the genomic DNA can be obtained directly from the patient...
13.
Analysis of major genome loci underlying artemisinin resistance and pfmdr1 copy number in pre- and post-ACTs in western Kenya
Ngalah B, Ingasia L, Cheruiyot A, Chebon L, Juma D, Muiruri P, et al.
Sci Rep . 2015 Feb; 5:8308. PMID: 25655315
Genetic analysis of molecular markers is critical in tracking the emergence and/or spread of artemisinin resistant parasites. Clinical isolates collected in western Kenya pre- and post- introduction of artemisinin combination...
14.
Five-year tracking of Plasmodium falciparum allele frequencies in a holoendemic area with indistinct seasonal transitions
Akala H, Achieng A, Eyase F, Juma D, Ingasia L, Cheruiyot A, et al.
J Multidiscip Healthc . 2014 Nov; 7:515-23. PMID: 25395861
Background: The renewed malaria eradication efforts require an understanding of the seasonal patterns of frequency of polymorphic variants in order to focus limited funds productively. Although cross-sectional studies in holoendemic...
15.
Reduced in vitro doxycycline susceptibility in plasmodium falciparum field isolates from Kenya is associated with PfTetQ KYNNNN sequence polymorphism
Achieng A, Ingasia L, Juma D, Cheruiyot A, Okudo C, Yeda R, et al.
Antimicrob Agents Chemother . 2014 Jul; 58(10):5894-9. PMID: 25070109
Doxycycline is widely used for malaria prophylaxis by international travelers. However, there is limited information on doxycycline efficacy in Kenya, and genetic polymorphisms associated with reduced efficacy are not well...
16.
Polymorphisms in Pfmdr1, Pfcrt, and Pfnhe1 genes are associated with reduced in vitro activities of quinine in Plasmodium falciparum isolates from western Kenya
Cheruiyot J, Ingasia L, Omondi A, Juma D, Opot B, Ndegwa J, et al.
Antimicrob Agents Chemother . 2014 Apr; 58(7):3737-43. PMID: 24752268
In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line treatment for severe malaria, and for treatment of malaria in the first trimester...
17.
Antimalarial drug sensitivity profile of western Kenya Plasmodium falciparum field isolates determined by a SYBR Green I in vitro assay and molecular analysis
Akala H, Eyase F, Cheruiyot A, Omondi A, Ogutu B, Waters N, et al.
Am J Trop Med Hyg . 2011 Jul; 85(1):34-41. PMID: 21734121
In vitro drug sensitivity and molecular analyses of Plasmodium falciparum track drug resistance. DNA-binding fluorescent dyes like SYBR Green I may allow field laboratories, proximal to P. falciparum collection sites,...