Adrian T Gonon
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Explore the profile of Adrian T Gonon including associated specialties, affiliations and a list of published articles.
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14
Citations
342
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Recent Articles
1.
Tratsiakovich Y, Kiss A, Gonon A, Yang J, Sjoquist P, Pernow J
Diab Vasc Dis Res
. 2017 Feb;
14(3):236-245.
PMID: 28183205
Aim: RhoA/Rho-associated kinase and arginase are implicated in vascular complications in diabetes. This study investigated whether RhoA/Rho-associated kinase and arginase inhibition protect from myocardial ischaemia-reperfusion injury in type 1 diabetes...
2.
Kiss A, Tratsiakovich Y, Gonon A, Fedotovskaya O, Lanner J, Andersson D, et al.
PLoS One
. 2014 Aug;
9(8):e104731.
PMID: 25140754
Background: Pharmacological inhibition of arginase and remote ischemic perconditioning (RIPerc) are known to protect the heart against ischemia/reperfusion (IR) injury. Purpose: The objective of this study was to investigate whether...
3.
Tratsiakovich Y, Gonon A, Kiss A, Yang J, Bohm F, Tornvall P, et al.
Int J Cardiol
. 2013 Sep;
169(1):83-8.
PMID: 24067598
Background: Reduced bioavailability of nitric oxide (NO) is a key factor contributing to myocardial ischemia and reperfusion injury. The mechanism behind the reduction of NO is related to deficiency of...
4.
Yang J, Gonon A, Sjoquist P, Lundberg J, Pernow J
Proc Natl Acad Sci U S A
. 2013 Aug;
110(37):15049-54.
PMID: 23980179
The theory that red blood cells (RBCs) generate and release nitric oxide (NO)-like bioactivity has gained considerable interest. However, it remains unclear whether it can be produced by endothelial NO...
5.
Gonon A, Jung C, Katz A, Westerblad H, Shemyakin A, Sjoquist P, et al.
PLoS One
. 2012 Aug;
7(7):e42038.
PMID: 22860052
Consumption of L-arginine contributes to reduced bioavailability of nitric oxide (NO) that is critical for the development of ischemia-reperfusion injury. The aim of the study was to determine myocardial arginase...
6.
Karlsson L, Grip L, Bissessar E, Bobrova I, Gustafsson T, Kavianipour M, et al.
Eur J Pharmacol
. 2010 Nov;
651(1-3):146-51.
PMID: 21093430
Eribis peptide 94 (EP 94) is a novel enkephalin analog, thought to interact with the μ- and δ-opioid receptors. The purpose of the present study was to examine the cardioprotective...
7.
Jung C, Gonon A, Sjoquist P, Lundberg J, Pernow J
Cardiovasc Res
. 2009 Sep;
85(1):147-54.
PMID: 19726439
Aims: Nitric oxide (NO) is vital for the integrity of the cardiovascular system and protection against ischaemic heart disease. Arginase is up-regulated during ischaemia-reperfusion (IR) and this enzyme might compete...
8.
Gonon A, Widegren U, Bulhak A, Salehzadeh F, Persson J, Sjoquist P, et al.
Cardiovasc Res
. 2008 Jan;
78(1):116-22.
PMID: 18222959
Aims: Cardiovascular disease and type 2 diabetes mellitus are associated with low plasma concentration of adiponectin. The aim of this study was to investigate whether adiponectin exerts cardioprotective effects during...
9.
Gonon A, Bulhak A, Labruto F, Sjoquist P, Pernow J
Basic Res Cardiol
. 2006 Aug;
102(1):80-9.
PMID: 16900441
Unlabelled: Activation of peroxisome proliferator-activated receptor (PPAR) gamma protects from myocardial ischemia/reperfusion injury. The aim of the study was to investigate whether the cardioprotective effect of PPARgamma is related to...
10.
Gonon A, Bulhak A, Broijersen A, Pernow J
Br J Pharmacol
. 2005 Feb;
144(6):860-6.
PMID: 15685207
1. Endothelin (ET) receptor antagonists are cardioprotective during myocardial ischaemia and reperfusion through a nitric oxide (NO)-dependent mechanism. The aim of the present study was to investigate whether the ET...