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Adrian P E Kromer

Explore the profile of Adrian P E Kromer including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Muller J, Kromer A, Ezaddoustdar A, Alexopoulos I, Steinegger K, Porras-Gonzalez D, et al.
ACS Appl Mater Interfaces . 2025 Feb; 17(8):11861-11872. PMID: 39938880
Biodegradable poly(β-amino) esters (PBAEs) have been a focus of interest for delivering therapeutic siRNA for several years. While no approved therapies are on the market yet, our study aims to...
2.
Steinegger K, Allmendinger L, Sturm S, Sieber-Schafer F, Kromer A, Muller-Caspary K, et al.
Nano Lett . 2024 Nov; 24(49):15683-15692. PMID: 39592142
Cationic polymers are known to efficiently deliver nucleic acids to target cells by encapsulating the cargo into nanoparticles. However, the molecular organization of these nanoparticles is often not fully explored....
3.
Kromer A, Sieber-Schafer F, Farfan Benito J, Merkel O
ACS Appl Mater Interfaces . 2024 Jul; 16(29):37545-37554. PMID: 38985802
Successful therapeutic delivery of siRNA with polymeric nanoparticles seems to be a promising but not vastly understood and complicated goal to achieve. Despite years of research, no polymer-based delivery system...
4.
Jin Y, Wang X, Kromer A, Muller J, Zimmermann C, Xu Z, et al.
Biomacromolecules . 2024 Jun; 25(7):4177-4191. PMID: 38866384
After RNAi was first discovered over 20 years ago, siRNA-based therapeutics are finally becoming reality. However, the delivery of siRNA has remained a challenge. In our previous research, we found...