Adrian Olmos-Alonso
Overview
Explore the profile of Adrian Olmos-Alonso including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
1008
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0
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Recent Articles
1.
Guerrero-Carrasco M, Targett I, Olmos-Alonso A, Vargas-Caballero M, Gomez-Nicola D
Glia
. 2024 Apr;
72(7):1340-1355.
PMID: 38597386
Several in vivo studies have shown that systemic inflammation, mimicked by LPS, triggers an inflammatory response in the CNS, driven by microglia, characterized by an increase in inflammatory cytokines and...
2.
Hu Y, Fryatt G, Ghorbani M, Obst J, Menassa D, Martin-Estebane M, et al.
Cell Rep
. 2021 Jun;
35(10):109228.
PMID: 34107254
The sustained proliferation of microglia is a key hallmark of Alzheimer's disease (AD), accelerating its progression. Here, we aim to understand the long-term impact of the early and prolonged microglial...
3.
Askew K, Li K, Olmos-Alonso A, Garcia-Moreno F, Liang Y, Richardson P, et al.
Cell Rep
. 2017 Jan;
18(2):391-405.
PMID: 28076784
Microglia play key roles in brain development, homeostasis, and function, and it is widely assumed that the adult population is long lived and maintained by self-renewal. However, the precise temporal...
4.
Martinez-Muriana A, Mancuso R, Francos-Quijorna I, Olmos-Alonso A, Osta R, Perry V, et al.
Sci Rep
. 2016 May;
6:25663.
PMID: 27174644
Inflammation is a common neuropathological feature in several neurological disorders, including amyotrophic lateral sclerosis (ALS). We have studied the contribution of CSF1R signalling to inflammation in ALS, as a pathway...
5.
Bisht K, Sharma K, Lecours C, Sanchez M, El Hajj H, Milior G, et al.
Glia
. 2016 Feb;
64(5):826-39.
PMID: 26847266
The past decade has witnessed a revolution in our understanding of microglia. These immune cells were shown to actively remodel neuronal circuits, leading to propose new pathogenic mechanisms. To study...
6.
Olmos-Alonso A, Schetters S, Sri S, Askew K, Mancuso R, Vargas-Caballero M, et al.
Brain
. 2016 Jan;
139(Pt 3):891-907.
PMID: 26747862
The proliferation and activation of microglial cells is a hallmark of several neurodegenerative conditions. This mechanism is regulated by the activation of the colony-stimulating factor 1 receptor (CSF1R), thus providing...
7.
de Lucia C, Rinchon A, Olmos-Alonso A, Riecken K, Fehse B, Boche D, et al.
Brain Behav Immun
. 2015 Nov;
55:179-190.
PMID: 26541819
Neurogenesis is altered in neurodegenerative disorders, partly regulated by inflammatory factors. We have investigated whether microglia, the innate immune brain cells, regulate hippocampal neurogenesis in neurodegeneration. Using the ME7 model...