Adrian L Slusarczyk
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Explore the profile of Adrian L Slusarczyk including associated specialties, affiliations and a list of published articles.
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9
Citations
304
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Recent Articles
1.
Desai M, Sharma J, Slusarczyk A, Chapin A, Ohlendorf R, Wisniowska A, et al.
Elife
. 2021 Dec;
10.
PMID: 34931988
Molecular imaging could have great utility for detecting, classifying, and guiding treatment of brain disorders, but existing probes offer limited capability for assessing relevant physiological parameters. Here, we describe a...
2.
Ohlendorf R, Wisniowska A, Desai M, Barandov A, Slusarczyk A, Li N, et al.
Nat Commun
. 2020 May;
11(1):2399.
PMID: 32404879
The ability to monitor molecules volumetrically throughout the body could provide valuable biomarkers for studies of healthy function and disease, but noninvasive detection of molecular targets in living subjects often...
3.
Desai M, Slusarczyk A, Chapin A, Barch M, Jasanoff A
Nat Commun
. 2016 Dec;
7:13607.
PMID: 27910951
In vivo imaging techniques are powerful tools for evaluating biological systems. Relating image signals to precise molecular phenomena can be challenging, however, due to limitations of the existing optical, magnetic...
4.
Slusarczyk A, Lin A, Weiss R
Nat Rev Genet
. 2012 May;
13(6):406-20.
PMID: 22596318
Synthetic gene circuits are designed to program new biological behaviour, dynamics and logic control. For all but the simplest synthetic phenotypes, this requires a structured approach to map the desired...
5.
Slusarczyk A, Weiss R
Sci Signal
. 2012 Apr;
5(220):pe16.
PMID: 22510466
Tissue-scale organization emerges from the action of sophisticated multiscale developmental programs. But the design rules for composing elementary signaling and information processing modules into such functional systems and for integrating...
6.
Orcutt K, Slusarczyk A, Cieslewicz M, Ruiz-Yi B, Bhushan K, Frangioni J, et al.
Nucl Med Biol
. 2011 Feb;
38(2):223-33.
PMID: 21315278
Introduction: In pretargeted radioimmunotherapy (PRIT), a bifunctional antibody is administered and allowed to pre-localize to tumor cells. Subsequently, a chelated radionuclide is administered and captured by cell-bound antibody while unbound...
7.
Lazos O, Tosin M, Slusarczyk A, Boakes S, Cortes J, Sidebottom P, et al.
Chem Biol
. 2010 Mar;
17(2):160-73.
PMID: 20189106
The genome of the erythromycin-producing bacterium Saccharopolyspora erythraea contains many orphan secondary metabolite gene clusters including two (nrps3 and nrps5) predicted to govern biosynthesis of nonribosomal peptide-based siderophores. We report...
8.
Neumann H, Slusarczyk A, Chin J
J Am Chem Soc
. 2010 Feb;
132(7):2142-4.
PMID: 20121121
The genetic code sets the correspondence between codons and the amino acids they encode in protein translation. The code is enforced by aminoacyl-tRNA synthetase/tRNA pairs, which direct the unique coupling...
9.
Orcutt K, Ackerman M, Cieslewicz M, Quiroz E, Slusarczyk A, Frangioni J, et al.
Protein Eng Des Sel
. 2009 Dec;
23(4):221-8.
PMID: 20019028
Here we present a bispecific antibody (bsAb) format in which a disulfide-stabilized scFv is fused to the C-terminus of the light chain of an IgG to create an IgG-scFv bifunctional...