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Adrian G Patterson

Explore the profile of Adrian G Patterson including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Hampton H, Patterson A, Chang J, Taylor C, Fineran P
FEMS Microbiol Lett . 2019 Jun; 366(11). PMID: 31226710
CRISPR-Cas adaptive immune systems protect bacteria from phage predation, and other foreign genetic elements such as plasmids. Significant advances have been made regarding how CRISPR-Cas systems elicit immunity; however, comparatively...
2.
Patterson A, Yevstigneyeva M, Fineran P
Curr Opin Microbiol . 2017 Apr; 37:1-7. PMID: 28359988
CRISPR-Cas systems are prokaryotic immune systems that allow defense against invasion by foreign genetic elements. Through the acquisition of genetic memory representing prior exposure, the CRISPR-Cas machinery identifies complementary nucleic...
3.
Patterson A, Jackson S, Taylor C, Evans G, Salmond G, Przybilski R, et al.
Mol Cell . 2016 Nov; 64(6):1102-1108. PMID: 27867010
Bacteria commonly exist in high cell density populations, making them prone to viral predation and horizontal gene transfer (HGT) through transformation and conjugation. To combat these invaders, bacteria possess an...
4.
Patterson A, Chang J, Taylor C, Fineran P
Nucleic Acids Res . 2015 May; 43(12):6038-48. PMID: 26007654
The CRISPR-Cas prokaryotic 'adaptive immune systems' represent a sophisticated defence strategy providing bacteria and archaea with protection from invading genetic elements, such as bacteriophages or plasmids. Despite intensive research into...