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Aditya A Mohan

Explore the profile of Aditya A Mohan including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 189
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Recent Articles
1.
Hurst J, Mohan A, Dalapati T, George I, Aquino J, Lugo D, et al.
Nat Commun . 2025 Mar; 16(1):2383. PMID: 40064870
Age is among the strongest risk factors for severe outcomes from SARS-CoV-2 infection. Here we describe upper respiratory tract (URT) and peripheral blood transcriptomes of 202 participants (age range of...
2.
Hurst J, Mohan A, Dalapati T, George I, Aquino J, Lugo D, et al.
medRxiv . 2023 Aug; PMID: 37577568
One Sentence Summary: Age is associated with distinct upper respiratory and peripheral blood transcriptional responses among children and adults with SARS-CoV-2 infection.
3.
Lerner E, Woroniecka K, DAnniballe V, Wilkinson D, Mohan A, Lorrey S, et al.
Nat Cancer . 2023 Aug; 4(9):1258-1272. PMID: 37537301
The accepted paradigm for both cellular and anti-tumor immunity relies upon tumor cell killing by CD8 T cells recognizing cognate antigens presented in the context of target cell major histocompatibility...
4.
Yuile A, Wei J, Mohan A, Hotchkiss K, Khasraw M
Cancers (Basel) . 2023 Jun; 15(10). PMID: 37345193
Gliomas are the most common primary brain malignancy and are universally fatal. Despite significant breakthrough in understanding tumor biology, treatment breakthroughs have been limited. There is a growing appreciation that...
5.
Mohan A, Olson L, Naqvi I, Morrison S, Kraft B, Chen L, et al.
Crit Care Explor . 2022 Dec; 4(12):e0799. PMID: 36506827
Design: Flow cytometry of fresh blood and multiplexed inflammatory chemokine measurements of sera were performed on samples collected longitudinally from our cohort. Aggregate impact of comorbid conditions was calculated with...
6.
Jakubowski C, Mohan A, Kamel I, Yarchoan M
JCO Precis Oncol . 2022 Jan; 4:825-828. PMID: 35050759
No abstract available.
7.
Yarchoan M, Cope L, Ruggieri A, Anders R, Noonan A, Goff L, et al.
J Clin Invest . 2021 Dec; 131(24). PMID: 34907910
BACKGROUNDMEK inhibitors have limited activity in biliary tract cancers (BTCs) as monotherapy but are hypothesized to enhance responses to programmed death ligand 1 (PD-L1) inhibition.METHODSThis open-label phase II study randomized...
8.
Singh K, Hotchkiss K, Mohan A, Reedy J, Sampson J, Khasraw M
J Immunother Cancer . 2021 Nov; 9(11). PMID: 34795007
Glioblastoma is the the most common primary brain tumor in adults. Onset of disease is followed by a uniformly lethal prognosis and dismal overall survival. While immunotherapies have revolutionized treatment...
9.
Singh K, Hotchkiss K, Patel K, Wilkinson D, Mohan A, Cook S, et al.
Cancers (Basel) . 2021 Nov; 13(21). PMID: 34771532
Glioblastoma is an immunologically 'cold' tumor, which are characterized by absent or minimal numbers of tumor-infiltrating lymphocytes (TILs). For those tumors that have been invaded by lymphocytes, they are profoundly...
10.
Ho W, Croessmann S, Lin J, Phyo Z, Charmsaz S, Danilova L, et al.
J Clin Invest . 2021 Jul; PMID: 34283806
Both epidemiologic and cellular studies in the context of autoimmune diseases have established that protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a key regulator of T cell receptor (TCR)...