Adelyne Chan
Overview
Explore the profile of Adelyne Chan including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
101
Followers
0
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Recent Articles
1.
Collins C, Baker S, Brown J, Zheng H, Chan A, Stenius U, et al.
Bioinformatics
. 2024 Jan;
40(1).
PMID: 38258418
Motivation: Scientific advances build on the findings of existing research. The 2001 publication of the human genome has led to the production of huge volumes of literature exploring the context-specific...
2.
Yin K, Patten D, Gough S, de Barros Goncalves S, Chan A, Olan I, et al.
Genes Dev
. 2022 May;
36(9-10):533-549.
PMID: 35618311
Senescence is a stress-responsive tumor suppressor mechanism associated with expression of the senescence-associated secretory phenotype (SASP). Through the SASP, senescent cells trigger their own immune-mediated elimination, which if evaded leads...
3.
Goncalves S, Yin K, Ito Y, Chan A, Olan I, Gough S, et al.
Cell Rep
. 2021 Mar;
34(11):108860.
PMID: 33730589
Senescent cells trigger their own immune-mediated destruction, termed senescence surveillance. This is dependent on the inflammatory senescence-associated secretory phenotype (SASP), which includes COX2, an enzyme with complex roles in cancer....
4.
Ariffin H, Azanan M, Abd Ghafar S, Oh L, Lau K, Thirunavakarasu T, et al.
Cancer
. 2017 Jun;
123(21):4207-4214.
PMID: 28654149
Background: Large epidemiologic studies have reported the premature onset of age-related conditions, such as ischemic heart disease and diabetes mellitus, in childhood cancer survivors, decades earlier than in their peers....