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Adeline Page

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Articles 34
Citations 1164
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Recent Articles
1.
Lavergne J, Page A, Polard P, Campo N, Grangeasse C
J Proteomics . 2025 Feb; 315:105399. PMID: 39921128
Competence in the pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) is a developmental genetic program that is key for natural genetic transformation and consequently bacterial horizontal gene transfer. Phosphoproteomic studies have...
2.
El Hajjar L, Page A, Bridot C, Cantrelle F, Landrieu I, Smet-Nocca C
Biochemistry . 2024 May; 63(12):1513-1533. PMID: 38788673
Glycogen synthase kinase 3 (GSK3) plays a pivotal role in signaling pathways involved in insulin metabolism and the pathogenesis of neurodegenerative disorders. In particular, the GSK3β isoform is implicated in...
3.
Wongdontree P, Millan-Oropeza A, Upfold J, Lavergne J, Halpern D, Lambert C, et al.
iScience . 2024 Apr; 27(4):109505. PMID: 38577105
Antibiotics inhibiting the fatty acid synthesis pathway (FASII) of the major pathogen reach their enzyme targets, but bacteria continue growth by using environmental fatty acids (eFAs) to produce phospholipids. We...
4.
Conchou L, Doumeche B, Galisson F, Violot S, Dugelay C, Diesis E, et al.
Commun Biol . 2022 Nov; 5(1):1158. PMID: 36316540
Metacaspases are caspase-like homologs which undergo a complex maturation process involving multiple intra-chain cleavages resulting in a composite enzyme made of a p10 and a p20 domain. Their proteolytic activity...
5.
Diagne A, Pelletier A, Durmort C, Faure A, Kanonenberg K, Freton C, et al.
PLoS Pathog . 2022 Apr; 18(4):e1010458. PMID: 35395062
Two-component regulatory systems (TCS) are among the most widespread mechanisms that bacteria use to sense and respond to environmental changes. In the human pathogen Streptococcus pneumoniae, a total of 13...
6.
Fogeron M, Lecoq L, Cole L, Montserret R, David G, Page A, et al.
Front Mol Biosci . 2022 Mar; 8:821755. PMID: 35282608
We here establish the phosphorylation sites in the human hepatitis B virus (HBV) large envelope protein (L). L is involved in several functionally important interactions in the viral life cycle,...
7.
Very N, Hardiville S, Decourcelle A, Thevenet J, Djouina M, Page A, et al.
Oncogene . 2021 Nov; 41(5):745-756. PMID: 34845374
Alteration of O-GlcNAcylation, a dynamic posttranslational modification, is associated with tumorigenesis and tumor progression. Its role in chemotherapy response is poorly investigated. Standard treatment for colorectal cancer (CRC), 5-fluorouracil (5-FU),...
8.
Dussoyer M, Page A, Delolme F, Rousselle P, Nystrom A, Moali C
J Proteomics . 2021 Oct; 251:104397. PMID: 34678517
A striking feature of skin organization is that the extracellular matrix (ECM) occupies a larger volume than the cells. Skin ECM also directly contributes to aging and most cutaneous diseases....
9.
Paget S, Dubuissez M, Page A, Dehennaut V, Loison I, Spruyt N, et al.
Biochem Biophys Res Commun . 2021 Mar; 553:51-57. PMID: 33756345
The tumor suppressor gene HIC1 (Hypermethylated in Cancer 1) encodes a transcriptional repressor involved in the DNA-damage response. A SUMOylation increase on HIC1 Lysine314 favors the direct transcriptional repression of...
10.
Florens N, Calzada C, Lemoine S, Boulet M, Guillot N, Barba C, et al.
J Am Soc Nephrol . 2020 Jun; 31(7):1462-1477. PMID: 32518085
Background: CKD is associated with increased oxidative stress that correlates with occurrence of cardiovascular events. Modifications induced by increased oxidative stress particularly affect circulating lipoproteins such as HDL that exhibit...