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» Authors » Adel A-H Abdel-Rahman

Adel A-H Abdel-Rahman

Explore the profile of Adel A-H Abdel-Rahman including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 31
Citations 106
Followers 0
Related Specialties
Biochemistry
Biology
Molecular Biology
Top 10 Co-Authors
Wael A El-Sayed
Nasser A Hassan
Mohammed F Hamza
Yuezhou Wei
Ibrahim F Zeid
Mahmoud S Khalafalla
Allam A Hassan
El Sayed H El Ashry
Omar M Ali
Nashwa M Saleh
Published In
Z Naturforsch C J Biosci
Molecules
Materials (Basel)
Arch Pharm (Weinheim)
Sci Rep
Affiliations
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Recent Articles
1.
Biosynthesized ZnO NPs loaded-electrospun PVA/sodium alginate/glycine nanofibers: synthesis, spinning optimization and antimicrobial activity evaluation
Kenawy E, Kamoun E, Shehata A, El-Moslamy S, Abdel-Rahman A
Sci Rep . 2025 Jan; 15(1):1882. PMID: 39805918
In this work, microalgae-based zinc oxide nanoparticles loaded with electrospun polyvinyl alcohol (PVA)/sodium alginate (SA) nanofibers were fabricated by electro-spinner. PVA/SA fibrous mats were crosslinked by citric acid, which enhanced...
2.
Rational design, synthesis, biological evaluation, molecular docking, and molecular dynamics of substituted uracil derivatives as potent anti-cancer agents
Basiony E, Hassan A, Elsawalhy M, Abdel-Rahman A, Mansour H, Arafa R, et al.
Bioorg Chem . 2024 Dec; 154:108066. PMID: 39718078
An efficient synthesis of a series of uracil analogous was performed to obtain new potential anticancer agents. The cytotoxic effect of the synthesized derivatives was assessed in vitro against three...
3.
Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors Based on the Pyridyl-Pyridazine Moiety for the Potential Treatment of Alzheimer's Disease
Elsawalhy M, Abdel-Rahman A, Basiony E, Ellithy S, Hassan A, Abou-Amra E, et al.
Pharmaceuticals (Basel) . 2024 Oct; 17(10). PMID: 39459045
: Alzheimer's disease (AD) is characterized by cholinergic dysfunction, making the inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) critical for improving cholinergic neurotransmission. However, the development of effective dual inhibitors...
4.
Novel quinazolin-4-one based derivatives bearing 1,2,3-triazole and glycoside moieties as potential cytotoxic agents through dual EGFR and VEGFR-2 inhibitory activity
Abdel-Rahman A, El-Bayaa M, Sobhy A, El-Ganzoury E, Nossier E, Awad H, et al.
Sci Rep . 2024 Oct; 14(1):24980. PMID: 39443462
The toxicity that was caused by the developed medications for anticancer treatment is, unfortunately, an earnest problem stemming from the various involved targets, and accordingly, intense research for overcoming such...
5.
Designing Potent Anti-Cancer Agents: Synthesis and Molecular Docking Studies of Thieno[2,3-][1,2,4]triazolo[1,5-]pyrimidine Derivatives
Elsenbawy E, Alshehri Z, Babteen N, Abdel-Rahman A, El-Manawaty M, Nossier E, et al.
Molecules . 2024 Mar; 29(5). PMID: 38474579
A new series of thieno[2,3-][1,2,4]triazolo[1,5-]pyrimidines was designed and synthesized using readily available starting materials, specifically, -enaminoester. Their cytotoxicity was screened against three cancer cell lines, namely, MCF-7, HCT-116, and PC-3....
6.
Study of the association between a gene polymorphism and cholangiocarcinoma in Egyptian patients
Abdel-Rahman A, Farag M, Naguib M, Abdelsameea E, Abdel-Bary H
Clin Exp Hepatol . 2023 Jan; 8(4):293-299. PMID: 36683874
Introduction: An inflammatory environment is the common pathway for the development of cholangiocarcinoma (CCA). The natural killer group 2D receptor (NKG2D), an activating receptor for NK cells, is a potent...
7.
Enhancement of Cerium Sorption onto Urea-Functionalized Magnetite Chitosan Microparticles by Sorbent Sulfonation-Application to Ore Leachate
Hamza M, Guibal E, Abdel-Rahman A, Salem M, Khalafalla M, Wei Y, et al.
Molecules . 2022 Nov; 27(21). PMID: 36364388
The recovery of strategic metals such as rare earth elements (REEs) requires the development of new sorbents with high sorption capacities and selectivity. The bi-functionality of sorbents showed a remarkable...
8.
Grafting of Thiazole Derivative on Chitosan Magnetite Nanoparticles for Cadmium Removal-Application for Groundwater Treatment
Hamza M, Abdel-Rahman A, Negm A, Hamad D, Khalafalla M, Fouda A, et al.
Polymers (Basel) . 2022 Mar; 14(6). PMID: 35335569
The synthesis and developments of magnetic chitosan nanoparticles for high efficiency removal of the cadmium ions from aquatic medium are one of the most challenging techniques. Highly adsorptive composite (MCH-ATA)...
9.
Design, synthesis, anticancer, and docking of some S- and/or N-heterocyclic derivatives as VEGFR-2 inhibitors
El-Adl K, Abdel-Rahman A, Omar A, Alswah M, Saleh N
Arch Pharm (Weinheim) . 2021 Dec; 355(2):e2100237. PMID: 34862655
Novel heterocyclic derivatives (4-22) were designed, synthesized, and evaluated against hepatocellular carcinoma type (HepG2) and breast cancer (MCF-7) cells, targeting the VEGFR-2 enzyme. Compounds 18, 10, 13, 11, and 14...
10.
Discovery of New Pyrazolopyridine, Furopyridine, and Pyridine Derivatives as CDK2 Inhibitors: Design, Synthesis, Docking Studies, and Anti-Proliferative Activity
Abdel-Rahman A, Shaban A, Nassar I, El-Kady D, Ismail N, Mahmoud S, et al.
Molecules . 2021 Jul; 26(13). PMID: 34206976
New pyridine, pyrazoloyridine, and furopyridine derivatives substituted with naphthyl and thienyl moieties were designed and synthesized starting from 6-(naphthalen-2-yl)-2-oxo-4-(thiophen-2-yl)-1,2-dihydropyridine-3-carbonitrile (). The chloro, methoxy, cholroacetoxy, imidazolyl, azide, and arylamino derivatives were...