Aday Gonzalez-Bakker
Overview
Explore the profile of Aday Gonzalez-Bakker including associated specialties, affiliations and a list of published articles.
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18
Citations
12
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Recent Articles
1.
Barot D, Upadhyay D, Vala D, Parmar M, Gonzalez-Bakker A, Khan A, et al.
Nat Prod Res
. 2025 Mar;
:1-7.
PMID: 40066777
is a member of the Rutaceae family and a source of diverse biological properties. Most studies have focused on the extract from the dried fruit pulp, but the fresh pulp...
2.
Parmar M, Das A, Vala D, Bhalodiya S, Patel C, Balachandran S, et al.
ACS Omega
. 2025 Mar;
10(7):7013-7026.
PMID: 40028097
Owing to the significant contribution of three-dimensional (3D) field-based QSAR toward hit optimization and accurately predicting the activities of small molecules, herein, the 3D-QSAR, in vitro antimicrobial, molecular docking, and...
3.
Puerta A, Gonzalez-Bakker A, Romanos E, Dominguez I, Martinez-Montiel M, Merino-Montiel P, et al.
Biochem Pharmacol
. 2025 Feb;
234:116807.
PMID: 39978689
Mitochondria-targeting drugs (mitocans) based on organic cations are emerging as powerful and selective cancer therapeutics. In this study, we have evaluated a novel series of oleanolic acid-derived mitocans, revealing nanomolar-range...
4.
Martinez-Montiel M, Arrighi G, Begines P, Gonzalez-Bakker A, Puerta A, Fernandes M, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940992
The selective inhibition of key enzymes, such as carbonic anhydrases (CAs IX and XII), which are overexpressed in cancer tissues, has emerged as a promising strategy in cancer research. However,...
5.
Sabotic J, Puerta A, Gonzalez-Bakker A, Karnicar K, Erzar E, Tumpej T, et al.
Int J Biol Macromol
. 2024 Dec;
294:139220.
PMID: 39732261
Glycosylation patterns represent an important signature of cancer cells that can be decoded by glycan-binding proteins, i.e., lectins. Fungal lectins have unique properties and diverse structural and glycan-recognition features. In...
6.
Janeiro A, Gonzalez-Bakker A, Padron J, Marques C
Molecules
. 2024 Dec;
29(23).
PMID: 39683703
The 3-component Passerini reaction (3CPR), discovered little more than 100 years ago, has been demonstrated in the last few decades to be a valuable tool for accessing structural diversity and...
7.
Begines P, Bonardi A, Giovannuzzi S, Nocentini A, Gratteri P, De Luca V, et al.
Chem Biol Interact
. 2024 Oct;
404:111284.
PMID: 39442681
The role of carbonic anhydrases isoforms (CAs) IX and XII in the pathogenesis and progression of many types of solid tumors is well known. In this context, selective CA inhibitors...
8.
Reyes C, Ardiles A, Anaissi-Afonso L, Gonzalez-Bakker A, Padron J, Jimenez I, et al.
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273417
To explore new compounds with antitumour activity, fifteen phenolic -tripterpenes isolated from Celastraceae species, , and , have been studied. Their chemical structures were elucidated through spectroscopic and spectrometric techniques,...
9.
Quintana V, Gonzalez-Bakker A, Khan A, Padron J, Davyt D, Padron J, et al.
Arch Pharm (Weinheim)
. 2024 Aug;
357(11):e2400431.
PMID: 39105404
A series of new hybrid compounds was prepared combining tetrahydropyran rings with different aromatic systems by means of a 1,2,3-triazole, using a building block strategy. The design of these structures...
10.
Marques C, Gonzalez-Bakker A, Padron J
Beilstein J Org Chem
. 2024 Jun;
20:1213-1220.
PMID: 38887573
Considering early-stage drug discovery programs, the Ugi four-component reaction is a valuable, flexible, and pivotal tool, facilitating the creation of two new amide bonds in a one-pot fashion to effectively...