Adam Wahida
Overview
Explore the profile of Adam Wahida including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
570
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Recent Articles
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Wahida A, George B, Kurzrock R
Med
. 2024 Dec;
5(12):1463-1465.
PMID: 39674173
Precision oncology aims to match the right drug(s) to the right patient. Equally important is ensuring that precision therapies are offered at the right time. Transformative, rather than incremental, outcome...
3.
Ito J, Nakamura T, Toyama T, Chen D, Berndt C, Poschmann G, et al.
Mol Cell
. 2024 Nov;
84(23):4629-4644.e9.
PMID: 39547222
Selenium-dependent glutathione peroxidase 4 (GPX4) is the guardian of ferroptosis, preventing unrestrained (phospho)lipid peroxidation by reducing phospholipid hydroperoxides (PLOOH). However, the contribution of other phospholipid peroxidases in ferroptosis protection remains...
4.
Wahida A, Kurzrock R
Oncologist
. 2024 Oct;
PMID: 39419766
Gene sequencing has brought a titanic of complex data into clinical precision oncology. Deciphering this complexity for practice requires new constructs. In 2014, the Molecular Tumor Board (MTB) was introduced...
5.
Hoeft K, Koch L, Ziegler S, Zhang L, Luetke S, Tanzer M, et al.
J Clin Invest
. 2024 Sep;
134(18).
PMID: 39286973
Fibrosis represents the uncontrolled replacement of parenchymal tissue with extracellular matrix (ECM) produced by myofibroblasts. While genetic fate-tracing and single-cell RNA-Seq technologies have helped elucidate fibroblast heterogeneity and ontogeny beyond...
6.
Wahida A, Buschhorn L
Med Genet
. 2024 Jun;
35(4):269-273.
PMID: 38835735
Monitoring ctDNA by liquid biopsies seems to represent the perfect match for precision oncology and its cornerstone clinical framework: the molecular tumour board (MTB). Detecting and scrutinising the success of...
7.
Seibt T, Wahida A, Hoeft K, Kemmner S, Linkermann A, Mishima E, et al.
Nephrol Dial Transplant
. 2024 Apr;
39(11):1754-1761.
PMID: 38684468
Ferroptosis is a regulated cell death modality triggered by iron-dependent lipid peroxidation. Ferroptosis plays a causal role in the pathophysiology of various diseases, making it a promising therapeutic target. Unlike...
8.
Nakamura T, Ito J, Mourao A, Wahida A, Nakagawa K, Mishima E, et al.
Cell Rep Methods
. 2024 Feb;
4(3):100710.
PMID: 38401540
Ferroptosis, a regulated cell death hallmarked by unrestrained lipid peroxidation, plays a pivotal role in the pathophysiology of various diseases, making it a promising therapeutic target. Glutathione peroxidase 4 (GPX4)...
9.
Wahida A, Schmaderer C, Buttner-Herold M, Branca C, Donakonda S, Haberfellner F, et al.
iScience
. 2023 Oct;
26(10):107879.
PMID: 37868627
Renal ischemia-reperfusion injury (IRI) is associated with reduced allograft survival, and each additional hour of cold ischemia time increases the risk of graft failure and mortality following renal transplantation. Receptor-interacting...
10.
Mishima E, Wahida A, Seibt T, Conrad M
Nat Metab
. 2023 Jun;
5(6):924-932.
PMID: 37337123
Vitamin K is essential for several physiological processes, such as blood coagulation, in which it serves as a cofactor for the conversion of peptide-bound glutamate to γ-carboxyglutamate in vitamin K-dependent...