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Adam Santaniello

Explore the profile of Adam Santaniello including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 2165
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Recent Articles
1.
Silverman H, Bostrom A, Nylander A, Akula A, Lazar A, Gomez R, et al.
Neurology . 2024 Dec; 104(2):e210228. PMID: 39715474
Background And Objective: The impact of menopause on the brain is not well understood. Hormonal changes, including puberty and pregnancy, influence the onset and course of multiple sclerosis (MS). After...
2.
Wade K, Suseno R, Kizer K, Williams J, Boquett J, Caillier S, et al.
Genome Biol . 2024 Oct; 25(1):274. PMID: 39420419
The extremely high levels of genetic polymorphism within the human major histocompatibility complex (MHC) limit the usefulness of reference-based alignment methods for sequence assembly. We incorporate a short-read, de novo...
3.
Wade K, Suseno R, Kizer K, Williams J, Boquett J, Caillier S, et al.
bioRxiv . 2024 Jun; PMID: 38826378
The extremely high levels of genetic polymorphism within the human major histocompatibility complex (MHC) limit the usefulness of reference-based alignment methods for sequence assembly. We incorporate a short read assembly...
4.
Chitnis T, Qureshi F, Gehman V, Becich M, Bove R, Cree B, et al.
Nat Commun . 2024 May; 15(1):4297. PMID: 38769309
The multifaceted nature of multiple sclerosis requires quantitative biomarkers that can provide insights related to diverse physiological pathways. To this end, proteomic analysis of deeply-phenotyped serum samples, biological pathway modeling,...
5.
Zamecnik C, Sowa G, Abdelhak A, Dandekar R, Bair R, Wade K, et al.
Nat Med . 2024 Apr; 30(5):1300-1308. PMID: 38641750
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. In this study, the Department of Defense Serum Repository (DoDSR), a cohort of...
6.
Chitnis T, Qureshi F, Gehman V, Becich M, Bove R, Cree B, et al.
medRxiv . 2023 Jul; PMID: 37461671
Background/objectives: Serum proteomic analysis of deeply-phenotyped samples, biological pathway modeling and network analysis were performed to elucidate the inflammatory and neurodegenerative processes of multiple sclerosis (MS) and identify sensitive biomarkers...
7.
Zamecnik C, Sowa G, Abdelhak A, Dandekar R, Bair R, Wade K, et al.
medRxiv . 2023 May; PMID: 37205595
Although B cells are implicated in multiple sclerosis (MS) pathophysiology, a predictive or diagnostic autoantibody remains elusive. Here, the Department of Defense Serum Repository (DoDSR), a cohort of over 10...
8.
Bove R, Poole S, Cuneo R, Gupta S, Sabatino Jr J, Harms M, et al.
Neurol Neuroimmunol Neuroinflamm . 2022 Dec; 10(2). PMID: 36585249
Background And Objectives: Prospective, deeply phenotyped research cohorts monitoring individuals with chronic neurologic conditions, such as multiple sclerosis (MS), depend on continued participant engagement. The COVID-19 pandemic restricted in-clinic research...
9.
Cordano C, Nourbakhsh B, Yiu H, Papinutto N, Caverzasi E, Abdelhak A, et al.
Neurology . 2022 Aug; 99(15):e1685-e1693. PMID: 36038272
Background And Objectives: The timing of neurodegeneration in multiple sclerosis (MS) remains unclear. It is critical to understand the dynamics of neuroaxonal loss if we hope to prevent or forestall...
10.
Kaplan T, Gopal A, Block V, Suskind A, Zhao C, Polgar-Turcsanyi M, et al.
Mult Scler Relat Disord . 2022 Apr; 62:103793. PMID: 35461057
Background: Neurogenic lower urinary tract dysfunction (LUTD) results in lower urinary tract symptoms (LUTS) that impact quality of life in people with multiple sclerosis (PwMS). The risk factors and the...