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Adam Penn-Nicholson

Explore the profile of Adam Penn-Nicholson including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 2424
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Recent Articles
1.
Chilambi G, Reiss R, Daivaa N, Banada P, De Vos M, Penn-Nicholson A, et al.
Microbiol Spectr . 2025 Jan; 13(3):e0240324. PMID: 39873526
Tongue swabs represent a potential alternative to sputum as a sample type for detecting pulmonary tuberculosis (TB) with molecular diagnostic tests. The methods used to process tongue swabs for testing...
2.
Auma E, Alberts R, Derendinger B, Venter R, Streicher E, Pillay S, et al.
Clin Infect Dis . 2024 Dec; PMID: 39663850
Background: Drug susceptibility testing (DST) is essential for starting people on effective tuberculosis (TB) regimens. No published data exists for the high-throughput LiquidArray MTB-XDR (LA-XDR) test, which detects Mycobacterium tuberculosis...
3.
Bezuidenhout C, Long L, Nichols B, Meyer-Rath G, Fox M, Olifant S, et al.
medRxiv . 2024 Nov; PMID: 39574838
Introduction: Effective strategies are needed to facilitate early detection and diagnosis of tuberculosis (TB). The overreliance on passive case detection, symptom screening, and collection of sputum, results in delayed or...
4.
Bezuidenhout C, Long L, Nichols B, Meyer-Rath G, Fox M, Theron G, et al.
medRxiv . 2024 Nov; PMID: 39484233
Background: Delayed and missed diagnosis are a persistent barrier to tuberculosis control, partly driven by limitations associated with sputum collection and an unmet need for decentralized testing. Household contact investigation...
5.
Fiore-Gartland A, Srivastava H, Seese A, Day T, Penn-Nicholson A, Luabeya A, et al.
Front Immunol . 2024 Oct; 15:1441944. PMID: 39381003
Introduction: Development of an effective vaccine against tuberculosis is a critical step towards reducing the global burden of disease. A therapeutic vaccine might also reduce the high rate of TB...
6.
Abdulgader S, Chiwaya A, Reeve B, Palmer Z, Mishra H, Mbu D, et al.
Res Sq . 2024 Sep; PMID: 39315266
Background: Truenat MTB Plus (MTB Plus) and MTB Ultima (Ultima) are World Health Organization-endorsed low-complexity tuberculosis (TB) tests, however, performance data are scarce. Methods: Adults (≥18 years; n=498) self-presenting with...
7.
Auma E, Alberts R, Derendinger B, Venter R, Streicher E, Pillay S, et al.
Res Sq . 2024 Aug; PMID: 39149464
Drug susceptibility testing (DST) is essential for effectively starting people on effective tuberculosis (TB) regimens. No accuracy data exists for the new high-throughput LiquidArray MTB-XDR (LA-XDR) test, which detects complex...
8.
Mangu C, Cossa M, Ndege R, Khosa C, Leukes V, de la Torre-Perez L, et al.
BMC Infect Dis . 2024 Aug; 24(1):831. PMID: 39148008
Introduction: Tuberculosis (TB) is an important cause of morbidity and mortality among people living with HIV (PLHIV). Current WHO-recommended strategies for diagnosing TB among hospitalized PLHIV rely on symptom screening...
9.
Chilambi G, Reiss R, Daivaa N, Banada P, De Vos M, Penn-Nicholson A, et al.
medRxiv . 2024 Jul; PMID: 38947094
Importance: Xpert MTB/RIF Ultra (Xpert Ultra) is approved by the World Health Organization for the diagnosis of tuberculosis (TB). This test is typically performed using sputum specimens obtained from people...
10.
Medina-Marino A, Bezuidenhout D, Bezuidenhout C, Facente S, Fourie B, Shin S, et al.
Open Forum Infect Dis . 2024 Jun; 11(6):ofae279. PMID: 38868309
Background: Household contact investigations are effective for finding tuberculosis (TB) cases but are hindered by low referral uptake for clinic-based evaluation and testing. We assessed the acceptability and feasibility of...