Adam N Rosenthal
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Explore the profile of Adam N Rosenthal including associated specialties, affiliations and a list of published articles.
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40
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1049
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Recent Articles
1.
Haran S, Chindera K, Sabry M, Wilkinson N, Arora R, Zubiak A, et al.
Cancers (Basel)
. 2024 Mar;
16(6).
PMID: 38539519
Background: Tissue-specificity for fimbrial fallopian tube ovarian carcinogenesis remains largely unknown in mutation carriers. We aimed to assess the cell autonomous and cell-nonautonomous implications of a germline mutation in the...
2.
Wei X, Sun L, Slade E, Fierheller C, Oxley S, Kalra A, et al.
JAMA Netw Open
. 2024 Feb;
7(2):e2355324.
PMID: 38334999
Importance: Pathogenic variants (PVs) in BRCA1, BRCA2, PALB2, RAD51C, RAD51D, and BRIP1 cancer susceptibility genes (CSGs) confer an increased ovarian cancer (OC) risk, with BRCA1, BRCA2, PALB2, RAD51C, and RAD51D...
3.
Barker V, Vlachodimitropoulou E, OBrien P, Iskaros J, Rosenthal A
Obstet Gynecol
. 2023 Nov;
142(6):1500-1503.
PMID: 37917945
Background: The cumulative lifetime risk of ovarian cancer is 16-68% and 11-30% in female BRCA1 and BRCA2 gene alteration carriers, respectively. Risk-reducing bilateral salpingo-oophorectomy (RRSO) is the only proven way...
4.
Herzog C, Jones A, Evans I, Reisel D, Olaitan A, Doufekas K, et al.
Int J Cancer
. 2023 Oct;
154(4):679-691.
PMID: 37861205
Analysis of cell-free DNA methylation (cfDNAme), alone or combined with CA125, could help to detect ovarian cancers earlier and may reduce mortality. We assessed cfDNAme in regions of ZNF154, C2CD4D...
5.
Bryan S, Lee J, Gunu R, Jones A, Olaitan A, Rosenthal A, et al.
Cancers (Basel)
. 2023 May;
15(9).
PMID: 37174056
Background: High-risk HPV infection is responsible for >99% of cervix cancers (CC). In persistent infections that lead to cancer, the tumour breaches the basement membrane, releasing HPV-DNA into the bloodstream...
6.
Hanson H, Kulkarni A, Loong L, Kavanaugh G, Torr B, Allen S, et al.
J Med Genet
. 2022 Nov;
60(5):417-429.
PMID: 36411032
Germline pathogenic variants (GPVs) in the cancer predisposition genes , , , , , , , and are identified in approximately 15% of patients with ovarian cancer (OC). While there...
7.
Philpott S, Raikou M, Manchanda R, Lockley M, Singh N, Scott M, et al.
J Med Genet
. 2022 Nov;
60(5):440-449.
PMID: 36319079
Background: Our study aimed to establish 'real-world' performance and cost-effectiveness of ovarian cancer (OC) surveillance in women with pathogenic germline variants who defer risk-reducing bilateral salpingo-oophorectomy (RRSO). Methods: Our study...
8.
Herzog C, Marin F, Jones A, Evans I, Reisel D, Redl E, et al.
J Clin Oncol
. 2022 Aug;
40(33):3828-3838.
PMID: 36001862
Purpose: Endometrial cancer (EC) incidence has been rising over the past 10 years. Delays in diagnosis reduce survival and necessitate more aggressive treatment. We aimed to develop and validate a...
9.
Tjandraprawira K, Olaitan A, Petrie A, Wilkinson N, Rosenthal A
Obstet Gynecol Int
. 2022 Apr;
2022:7955290.
PMID: 35371262
Objective: To investigate conservative and excisional/ablative treatment outcomes for cervical intraepithelial neoplasia grade 2 (CIN2) following introduction of virological test of cure. Methods: This was a retrospective study of prospectively...
10.
Dawson H, Smrke A, Ellery P, Wilkinson N, Rosenthal A, McVeigh T
Fam Cancer
. 2021 Sep;
21(3):363-368.
PMID: 34524588
PTEN is a tumour suppressor gene involved in regulating cell division. Pathogenic germline variants in PTEN predispose to benign and malignant growths of numerous organs, including of the breast. In...