Adam M Benham
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Explore the profile of Adam M Benham including associated specialties, affiliations and a list of published articles.
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30
Citations
732
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Recent Articles
1.
Tan C, Morenc M, Setiawan M, Lim Z, Soon A, Bierman J, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125721
-hydroxycinnamic acid (pHCA) is one of the most abundant naturally occurring hydroxycinnamic acids, a class of chemistries known for their antioxidant properties. In this study, we evaluated the impact of...
2.
Fernandes S, Ferreira L, Benham A, Avellar M
Andrology
. 2024 Aug;
PMID: 39087751
Background: The endoplasmic reticulum (ER) is the central hub for protein quality control, where the protein disulfide isomerases (PDIs), encoded by at least 21 genes, play a pivotal role. These...
3.
Young N, Gui Z, Mustafa S, Papa K, Jessop E, Ruddell E, et al.
Cells
. 2024 Jun;
13(11.
PMID: 38891038
Eukaryotic cells tether the nucleoskeleton to the cytoskeleton via a conserved molecular bridge, called the LINC complex. The core of the LINC complex comprises SUN-domain and KASH-domain proteins that directly...
4.
Fang B, Card P, Chen J, Li L, Laughlin T, Jarrold B, et al.
Int J Mol Sci
. 2022 Jun;
23(11).
PMID: 35682565
Sallow and/or dull skin appearance is greatly attributable to the yellow components of skin tone. Bilirubin is a yellow chromophore known to be made in the liver and/or spleen and...
5.
Hunter-Featherstone E, Young N, Chamberlain K, Cubillas P, Hulette B, Wei X, et al.
Cells
. 2021 Jun;
10(5).
PMID: 34066027
Mechanotransduction is defined as the ability of cells to sense mechanical stimuli from their surroundings and translate them into biochemical signals. Epidermal keratinocytes respond to mechanical cues by altering their...
6.
Worfolk J, Bell S, Simpson L, Carne N, Francis S, Engelbertsen V, et al.
Antioxid Redox Signal
. 2019 Aug;
31(15):1117-1132.
PMID: 31436131
AGR2 is a tissue-restricted member of the protein disulfide isomerase family that has attracted interest because it is highly expressed in a number of cancers, including gastroesophageal adenocarcinoma. The behavior...
7.
Carne N, Bell S, Brown A, Maatta A, Flagler M, Benham A
Mol Cell Proteomics
. 2019 Mar;
18(6):1123-1137.
PMID: 30890563
Redox stress is a well-known contributor to aging and diseases in skin. Reductants such as dithiothreitol (DTT) can trigger a stress response by disrupting disulfide bonds. However, the quantitative response...
8.
Benham A
FEBS J
. 2018 Aug;
286(2):311-321.
PMID: 30062765
The Endoplasmic Reticulum (ER) is the major site for secretory protein production in eukaryotic cells and like an efficient factory, it has the capacity to expand or contract its output...
9.
Tokuhiro K, Satouh Y, Nozawa K, Isotani A, Fujihara Y, Hirashima Y, et al.
Sci Rep
. 2015 Sep;
5:14254.
PMID: 26388295
Calnexin (CANX) and calreticulin (CALR) chaperones mediate nascent glycoprotein folding in the endoplasmic reticulum. Here we report that these chaperones have distinct roles in male and female fertility. Canx null...
10.
Tarran W, Freeman G, Murphy L, Benham A, Kataky R, Williams J
Inorg Chem
. 2014 May;
53(11):5738-49.
PMID: 24848618
A new family of platinum(II) complexes of the form PtL(n)SR have been prepared, where L(n) represents a cyclometalating, N^C^N-bound tridentate ligand and SR is a monodentate thiolate ligand. The complexes...