Adam L Vanarsdall
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Explore the profile of Adam L Vanarsdall including associated specialties, affiliations and a list of published articles.
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21
Citations
817
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Recent Articles
1.
Vanarsdall A, Chin A, Liu J, Jardetzky T, Mudd J, Orloff S, et al.
Proc Natl Acad Sci U S A
. 2019 Feb;
116(9):3728-3733.
PMID: 30733288
Human cytomegalovirus (HCMV) causes substantial disease in transplant patients and harms the development of the nervous system in babies infected in utero. Thus, there is a major focus on developing...
2.
Liu J, Jardetzky T, Chin A, Johnson D, Vanarsdall A
J Virol
. 2018 Aug;
92(21).
PMID: 30111564
Human cytomegalovirus (HCMV) infects a wide variety of human cell types by different entry pathways that involve distinct envelope glycoprotein complexes that include gH/gL, a trimer complex consisting of gHgL/gO,...
3.
Vanarsdall A, Pritchard S, Wisner T, Liu J, Jardetzky T, Johnson D
mBio
. 2018 May;
9(3).
PMID: 29739904
Human cytomegalovirus (HCMV) replicates in many diverse cell types , and entry into different cells involves distinct entry mechanisms and different envelope glycoproteins. HCMV glycoprotein gB is thought to act...
4.
Murray S, Nesterenko P, Vanarsdall A, Munks M, Smart S, Veziroglu E, et al.
J Exp Med
. 2017 Jun;
214(7):1889-1899.
PMID: 28566275
Cytomegalovirus (CMV)-based vaccines have shown remarkable efficacy in the rhesus macaque model of acquired immune deficiency syndrome, enabling 50% of vaccinated monkeys to clear a subsequent virulent simian immunodeficiency virus...
5.
Chou S, Ercolani R, Vanarsdall A
J Clin Microbiol
. 2017 Apr;
55(7):2098-2104.
PMID: 28446569
Diagnostic mutations in the cytomegalovirus UL97 kinase gene are used to assess the level of associated ganciclovir resistance and therapeutic options. The best-known mutations at codons 460, 520, or 591...
6.
Vanarsdall A, Howard P, Wisner T, Johnson D
PLoS Pathog
. 2016 Apr;
12(4):e1005564.
PMID: 27082872
Human cytomegalovirus (HCMV) is a ubiquitous virus that is a major pathogen in newborns and immunocompromised or immunosuppressed patients. HCMV infects a wide variety of cell types using distinct entry...
7.
Vanarsdall A, Wisner T, Lei H, Kazlauskas A, Johnson D
PLoS Pathog
. 2012 Oct;
8(9):e1002905.
PMID: 23028311
Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor-α (PDGFRα) were reported to mediate entry of HCMV, including HCMV lab strain AD169. AD169 cannot assemble gH/gL/UL128-131, a glycoprotein complex...
8.
Vanarsdall A, Johnson D
Curr Opin Virol
. 2012 Mar;
2(1):37-42.
PMID: 22440964
No abstract available.
9.
Vanarsdall A, Chase M, Johnson D
J Virol
. 2011 Sep;
85(22):11638-45.
PMID: 21880752
A complex of five human cytomegalovirus virus (HCMV) proteins, gH, gL, UL128, UL130, and UL131 (gH/gL/UL128-131), is essential for virus entry into epithelial cells. We previously showed that gH/gL/UL128-131 expressed...
10.
Jin L, Carpenter D, Moerdyk-Schauwecker M, Vanarsdall A, Osorio N, Hsiang C, et al.
J Neurovirol
. 2008 Nov;
14(5):389-400.
PMID: 18989818
Latency-associated transcript (LAT) deletion mutants of herpes simplex virus type 1 (HSV-1) have reduced reactivation phenotypes. Thus, LAT plays an essential role in the latency-reactivation cycle of HSV-1. We have...