Adam J Hyman
Overview
Explore the profile of Adam J Hyman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
6
Citations
673
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Parsonage G, Cuthbertson K, Endesh N, Murciano N, Hyman A, Revill C, et al.
Br J Pharmacol
. 2022 Dec;
180(16):2039-2063.
PMID: 36457143
Background And Purpose: The protein PIEZO1 forms mechanically activated, calcium-permeable, non-selective cation channels in numerous cell types from several species. Options for pharmacological modulation are limited and so we modified...
2.
Chong J, De Vecchis D, Hyman A, Povstyan O, Ludlow M, Shi J, et al.
Biophys J
. 2021 Feb;
120(8):1343-1356.
PMID: 33582137
Piezo1 forms a mechanically activated calcium-permeable nonselective cation channel that is functionally important in many cell types. Structural data exist for C-terminal regions, but we lack information about N-terminal regions...
3.
Shi J, Hyman A, De Vecchis D, Chong J, Lichtenstein L, Simon Futers T, et al.
Cell Rep
. 2020 Oct;
33(1):108225.
PMID: 33027663
Endogenous PIEZO1 channels of native endothelium lack the hallmark inactivation often seen when these channels are overexpressed in cell lines. Because prior work showed that the force of shear stress...
4.
Evans E, Cuthbertson K, Endesh N, Rode B, Blythe N, Hyman A, et al.
Br J Pharmacol
. 2018 Mar;
175(10):1744-1759.
PMID: 29498036
Background And Purpose: The mechanosensitive Piezo1 channel has important roles in vascular physiology and disease. Yoda1 is a small-molecule agonist, but the pharmacology of these channels is otherwise limited. Experimental...
5.
Webster P, Littlejohns A, Gaunt H, Young R, Rode B, Ritchie J, et al.
Oncotarget
. 2017 Feb;
8(26):42288-42299.
PMID: 28178688
Surgical resection of colorectal cancer liver metastases (CLM) can be curative, yet 80% of patients are unsuitable for this treatment. As angiogenesis is a determinant of CLM progression we isolated...
6.
Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow M, et al.
Nature
. 2014 Aug;
515(7526):279-282.
PMID: 25119035
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic. Studies of sensory neurons have suggested Piezo proteins as subunits...