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Adam Hedberg-Buenz

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Citations 412
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Recent Articles
1.
McDowell C, Dutca L, Thompson S, Riker M, Hedberg-Buenz A, Meyer K, et al.
Exp Eye Res . 2025 Feb; 252:110266. PMID: 39894294
Intraocular pressure (IOP) follows a circadian rhythm. In both humans and mice, IOP is normally slightly elevated at night during the dark phase of the light cycle. In studying a...
2.
Hedberg-Buenz A, Boese E, Nyunt A, Sears N, Pouw A, Wang K, et al.
BMC Ophthalmol . 2025 Jan; 25(1):46. PMID: 39856599
Background: Endothelin is a potent vasoconstrictor and contributes to the regulation of vascular perfusion. Aberrant endothelin-1 (ET-1) levels in aqueous humor have been reported across a variety of vascular diseases...
3.
Wong C, Fraticelli Guzman N, Read A, Hedberg-Buenz A, Anderson M, Feola A, et al.
J Biomech . 2024 Apr; 168:112113. PMID: 38648717
Atomic force microscopy (AFM) is a valuable tool for assessing mechanical properties of biological samples, but interpretations of measurements on whole tissues can be difficult due to the tissue's highly...
4.
Wong C, Fraticelli Guzman N, Read A, Hedberg-Buenz A, Anderson M, Feola A, et al.
bioRxiv . 2023 Nov; PMID: 38014311
Atomic force microscopy (AFM) is a valuable tool for assessing mechanical properties of biological samples, but interpretations of measurements on whole tissues can be difficult due to the tissue's highly...
5.
Goyal V, Read A, Ritch M, Hannon B, Sanchez Rodriguez G, Brown D, et al.
Transl Vis Sci Technol . 2023 Mar; 12(3):9. PMID: 36917117
Purpose: Assessment of glaucomatous damage in animal models is facilitated by rapid and accurate quantification of retinal ganglion cell (RGC) axonal loss and morphologic change. However, manual assessment is extremely...
6.
Hedberg-Buenz A, Meyer K, van der Heide C, Deng W, Lee K, Soukup D, et al.
Transl Vis Sci Technol . 2022 Sep; 11(9):17. PMID: 36135979
Purpose: Despite popularity of optical coherence tomography (OCT) in glaucoma studies, it's unclear how well OCT-derived metrics compare to traditional measures of retinal ganglion cell (RGC) abundance. Here, Diversity Outbred...
7.
Meyer K, Pellack D, Hedberg-Buenz A, Pomernackas N, Soukup D, Wang K, et al.
Mol Vis . 2022 Feb; 27:741-756. PMID: 35136346
Purpose: Ocular tissues of mice have been studied in many ways using replication-deficient species C type 5 adenovirus (Ad5) as a tool for manipulating gene expression. Whereas refinements to injection...
8.
Deng W, Hedberg-Buenz A, Soukup D, Taghizadeh S, Wang K, Anderson M, et al.
Transl Vis Sci Technol . 2021 Dec; 10(14):22. PMID: 34932117
Purpose: Optic nerve damage is the principal feature of glaucoma and contributes to vision loss in many diseases. In animal models, nerve health has traditionally been assessed by human experts...
9.
van der Heide C, Meyer K, Hedberg-Buenz A, Pellack D, Pomernackas N, Mercer H, et al.
Exp Eye Res . 2021 Oct; 212:108774. PMID: 34597676
The nee mouse model exhibits characteristic features of congenital glaucoma, a common cause of childhood blindness. The current study of nee mice had two components. First, the time course of...
10.
Jiang J, Reho J, Bhattarai S, Cherascu I, Hedberg-Buenz A, Meyer K, et al.
Mol Metab . 2021 Jul; 53:101308. PMID: 34303879
Objectives: Endothelial cells that line the entire vascular system play a pivotal role in the control of various physiological processes, including metabolism. Additionally, endothelial dysfunction is associated with many pathological...