Adam Hedberg-Buenz
Overview
Explore the profile of Adam Hedberg-Buenz including associated specialties, affiliations and a list of published articles.
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30
Citations
412
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Recent Articles
11.
Boehme N, Hedberg-Buenz A, Tatro N, Bielecki M, Castonguay W, Scheetz T, et al.
Sci Rep
. 2021 Jun;
11(1):11774.
PMID: 34083587
Traumatic brain injuries (TBI) of varied types are common across all populations and can cause visual problems. For military personnel in combat settings, injuries from blast exposures (bTBI) are prevalent...
12.
Cring M, Meyer K, Searby C, Hedberg-Buenz A, Cave M, Anderson M, et al.
Gene Ther
. 2021 Mar;
29(5):227-235.
PMID: 33664503
Bardet-Biedl syndrome (BBS) is a rare ciliopathy for which there are no current effective treatments. BBS is a genetically heterogeneous disease, though the M390R mutation in BBS1 is involved in...
13.
Evans L, Woll A, Wu S, Todd B, Hehr N, Hedberg-Buenz A, et al.
J Neurotrauma
. 2020 Feb;
37(12):1463-1480.
PMID: 32056479
The purpose of this study was to characterize acute changes in inflammatory pathways in the mouse eye after blast-mediated traumatic brain injury (bTBI) and to determine whether modulation of these...
14.
Harper M, Woll A, Evans L, Delcau M, Akurathi A, Hedberg-Buenz A, et al.
Invest Ophthalmol Vis Sci
. 2019 Oct;
60(13):4159-4170.
PMID: 31598627
Purpose: The purpose of this study was to examine the effect of multiple blast exposures and blast preconditioning on the structure and function of retinal ganglion cells (RGCs), to identify...
15.
Harper M, Hedberg-Buenz A, Herlein J, Abrahamson E, Anderson M, Kuehn M, et al.
Invest Ophthalmol Vis Sci
. 2019 Jun;
60(7):2716-2725.
PMID: 31247112
Purpose: Traumatic brain injury (TBI) is a risk factor for developing chronic neurodegenerative conditions including Alzheimer's disease (AD). The purpose of this study was to examine chronic effects of blast...
16.
Hedberg-Buenz A, Dutca L, Larson D, Meyer K, Soukup D, van der Heide C, et al.
Sci Rep
. 2019 May;
9(1):6752.
PMID: 31043676
Chédiak-Higashi syndrome (CHS) is a lethal disorder caused by mutations in the LYST gene that involves progressive neurologic dysfunction. Lyst-mutant mice exhibit neurologic phenotypes that are sensitive to genetic background....
17.
Anderson M, Meyer K, Hedberg-Buenz A, Fingert J
J Glaucoma
. 2018 Feb;
27 Suppl 1:S78-S82.
PMID: 29419647
Animal models are powerful tools for studying diseases that affect the eye, such as exfoliation syndrome (XFS). Two types of animal models have been used to investigate the pathophysiology of...
18.
Wang C, Brancusi F, Valivullah Z, Anderson M, Cunningham D, Hedberg-Buenz A, et al.
Ophthalmic Genet
. 2017 Jul;
39(1):41-45.
PMID: 28742462
Purpose: To develop a sensitive scale of iris transillumination suitable for clinical and research use, with the capability of either quantitative analysis or visual matching of images. Methods: Iris transillumination...
19.
Lewis C, Hedberg-Buenz A, DeLuca A, Stone E, Alward W, Fingert J
Hum Mol Genet
. 2017 May;
26(R1):R28-R36.
PMID: 28549150
Glaucoma is the leading cause of irreversible blindness worldwide. Although most glaucoma patients are elderly, congenital glaucoma and glaucomas of childhood are also important causes of visual disability. Primary congenital...
20.
Fingert J, Miller K, Hedberg-Buenz A, Roos B, Lewis C, Mullins R, et al.
Hum Mol Genet
. 2016 Dec;
26(1):124-132.
PMID: 28025332
Duplication of the TBK1 gene is associated with 1-2% of normal tension glaucoma, a common cause of vision loss and blindness that occurs without grossly abnormal intraocular pressure. We generated...