Adam E Sundby
Overview
Explore the profile of Adam E Sundby including associated specialties, affiliations and a list of published articles.
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5
Citations
94
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Recent Articles
1.
Lautert-Dutra W, M Melo C, Chaves L, Souza F, Crozier C, Sundby A, et al.
Front Oncol
. 2023 Nov;
13:1280943.
PMID: 37965470
The diverse clinical outcomes of prostate cancer have led to the development of gene signature assays predicting disease progression. Improved prostate cancer progression biomarkers are needed as current RNA biomarker...
2.
Seroussi U, Lugowski A, Wadi L, Lao R, Willis A, Zhao W, et al.
Elife
. 2023 Feb;
12.
PMID: 36790166
Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode contains an expanded family of 19 functional AGO proteins, many of which have...
3.
Seroussi U, Li C, Sundby A, Lee T, Claycomb J, Saltzman A
Semin Cell Dev Biol
. 2021 Dec;
127:142-154.
PMID: 34876343
RNA interference (RNAi) is a highly conserved gene regulatory phenomenon whereby Argonaute/small RNA (AGO/sRNA) complexes target transcripts by antisense complementarity to modulate gene expression. While initially appreciated as a cytoplasmic...
4.
Charlesworth A, Seroussi U, Lehrbach N, Renaud M, Sundby A, Molnar R, et al.
Nucleic Acids Res
. 2021 Jul;
49(15):8836-8865.
PMID: 34329465
The Caenorhabditis elegans genome encodes nineteen functional Argonaute proteins that use 22G-RNAs, 26G-RNAs, miRNAs or piRNAs to regulate target transcripts. Only one Argonaute is essential under normal laboratory conditions: CSR-1....
5.
Sundby A, Molnar R, Claycomb J
Trends Cell Biol
. 2021 Feb;
31(5):387-401.
PMID: 33526340
Germ granules are non-membrane bound, phase-separated organelles, composed of RNAs and proteins. Germ granules are present only within the germ cells of animals, including model systems such as Caenorhabditis elegans,...