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Abu Shadat M Noman

Explore the profile of Abu Shadat M Noman including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 178
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Recent Articles
1.
Islam S, Karakas B, Aboussekhra A, Noman A
Cancers (Basel) . 2023 Oct; 15(20). PMID: 37894373
Mutations in / in head and neck cancer result in abnormal cell growth. Progenitor cells, bulk tumor cells, and head and neck cancer stem cells (HN-CSCs) may all harbor these...
2.
Ritch S, Noman A, Goyeneche A, Telleria C
Cancer Cell Int . 2022 Dec; 22(1):397. PMID: 36494669
Background: Simplistic two-dimensional (2D) in vitro assays have long been the standard for studying the metastatic abilities of cancer cells. However, tri-dimensional (3D) organotypic models provide a more complex environment,...
3.
Islam S, Qassem K, Islam S, Parag R, Rahman M, Farhat W, et al.
Cell Death Dis . 2022 Aug; 13(8):696. PMID: 35945195
Keap1 mutations regulate Nrf2 activity and lead to chemoresistance in cancers. Yet the underlying molecular mechanisms of chemoresistance are poorly explored. By focusing and genotyping head and neck squamous cell...
4.
Al-Mozaini M, Islam M, Noman A, Karim A, Farhat W, Yeger H, et al.
Front Med (Lausanne) . 2022 Apr; 9:835098. PMID: 35360723
Background: Patients recovering from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection demonstrate impaired lung function and those requiring chemotherapy after recovering from SARS-CoV-2 infection have yet to be explored....
5.
Al-Mozaini M, Noman A, Alotaibi J, Karim M, Zahed A, Karim A, et al.
Front Oncol . 2021 Sep; 11:715794. PMID: 34490115
The correlation between severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) viral load and risk of disease severity in cancer patients is poorly understood. Given the fact that cancer patients are at...
6.
Ali M, Oliva C, Noman A, Allen B, Goswami P, Zakharia Y, et al.
Cancers (Basel) . 2020 Sep; 12(9). PMID: 32899427
Ionizing radiation is a common and effective therapeutic option for the treatment of glioblastoma (GBM). Unfortunately, some GBMs are relatively radioresistant and patients have worse outcomes after radiation treatment. The...
7.
Noman A, Parag R, Rashid M, Islam S, Rahman M, Chowdhury A, et al.
Cell Death Dis . 2020 Aug; 11(8):663. PMID: 32814771
Overexpression of epithelial cell adhesion molecule (EpCAM) has been associated with chemotherapeutic resistance, leads to aggressive tumor behavior, and results in an adverse clinical outcome. The molecular mechanism by which...
8.
Noman A, Parag R, Rashid M, Rahman M, Chowdhury A, Sultana A, et al.
Ther Adv Med Oncol . 2020 Mar; 12:1758835920911229. PMID: 32206093
Background: Sonic hedgehog (Shh) and Nrf2 play a critical role in chemotherapeutic resistance. These two genes have been found to be dysregulated in head and neck squamous cell carcinomas (HNSCC)....
9.
Islam S, Uddin M, Noman A, Akter H, Dity N, Basiruzzman M, et al.
EBioMedicine . 2019 May; 43:211-224. PMID: 31085100
Background: A newly developed drug trastuzumab emtansine (T-DM1) has improved the survival of breast cancer (BC) patients. Despite an impressive initial clinical response, a subgroup of patient develop resistance and...
10.
Wu S, Dole K, Hong F, Noman A, Issacs J, Liu B, et al.
J Biol Chem . 2012 Apr; 287(24):19896-903. PMID: 22532561
HSP90 chaperones a large number of proteins, and it plays essential roles in multiple signaling pathways to maintain protein homeostasis in the cytosol. In addition, HSP90 has been implicated in...