Abraham Madariaga-Mazon
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Explore the profile of Abraham Madariaga-Mazon including associated specialties, affiliations and a list of published articles.
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24
Citations
172
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Recent Articles
1.
Antidiabetic Potential of a Trimeric Anthranilic Acid Peptide Isolated from Malbranchea flocciformis
Rebollar-Ramos D, Ovalle-Magallanes B, Raja H, Jacome-Rebollo M, Figueroa M, Tovar-Palacio C, et al.
Chem Biodivers
. 2023 Dec;
21(2):e202301602.
PMID: 38102075
Compound 3, a trimeric anthranilic acid peptide, and another three metabolites were isolated from an organic extract from the culture medium of Malbranchea flocciformis ATCC 34530. The chemical structure proposed...
2.
Diaz-Rojas M, Gonzalez-Andrade M, Aguayo-Ortiz R, Rodriguez-Sotres R, Perez-Vasquez A, Madariaga-Mazon A, et al.
Front Pharmacol
. 2023 Nov;
14:1281045.
PMID: 38027024
This work aimed to discover protein tyrosine phosphatase 1B (PTP1B) inhibitors from a small molecule library of natural products (NPs) derived from selected Mexican medicinal plants and fungi to find...
3.
Madariaga-Mazon A, Naveja J, Becerra A, Campillo-Balderas J, Hernandez-Morales R, Jacome R, et al.
Comput Struct Biotechnol J
. 2022 Sep;
20:5181-5192.
PMID: 36097553
The rapid spread and public health impact of the novel SARS-CoV-2 variants that cause COVID-19 continue to produce major global impacts and social distress. Several vaccines were developed in record...
4.
Perez-Vasquez A, Diaz-Rojas M, Castillejos-Ramirez E, Perez-Esquivel A, Montano-Cruz Y, Rivero-Cruz I, et al.
Phytochemistry
. 2022 Aug;
203:113410.
PMID: 36030904
An infusion from the aerial parts of Justicia spicigera Schltdl., an herb commonly used to treat diabetes, inhibited the activity of protein tyrosine phosphatase 1B (PTP1B). Two undescribed compounds, 2-N-(p-coumaroyl)-3H-phenoxazin-3-one,...
5.
Madariaga-Mazon A, Naveja J, Medina-Franco J, Noriega-Colima K, Martinez-Mayorga K
RSC Adv
. 2022 Apr;
11(9):5172-5178.
PMID: 35424427
Natural products are an invaluable source of molecules with a large variety of biological activities. Interest in natural products in drug discovery is documented in an increasing number of publications...
6.
Hernandez-Alvarado R, Madariaga-Mazon A, Cosme-Vela F, Marmolejo-Valencia A, Nefzi A, Martinez-Mayorga K
J Comput Aided Mol Des
. 2021 Oct;
35(11):1081-1093.
PMID: 34713377
Opioids are potent painkillers, however, their therapeutic use requires close medical monitoring to diminish the risk of severe adverse effects. The G-protein biased agonists of the μ-opioid receptor (MOR) have...
7.
Rosas-Jimenez J, Garcia-Revilla M, Madariaga-Mazon A, Martinez-Mayorga K
ACS Omega
. 2021 Mar;
6(10):6722-6735.
PMID: 33748586
Chagas disease affects 8-11 million people worldwide, most of them living in Latin America. Moreover, migratory phenomena have spread the infection beyond endemic areas. Efforts for the development of new...
8.
Hernandez-Alvarado R, Madariaga-Mazon A, Ortega A, Martinez-Mayorga K
ACS Chem Neurosci
. 2020 Nov;
11(23):3979-3992.
PMID: 33164503
Salvinorin A is the main bioactive compound in , an endemic plant with ancestral use by the inhabitants of the Mazateca mountain range (Sierra Mazateca) in Oaxaca, México. The main...
9.
Naveja J, Madariaga-Mazon A, Flores-Murrieta F, Granados-Montiel J, Maradiaga-Cecena M, Alaniz V, et al.
Drug Discov Today
. 2020 Oct;
26(1):229-239.
PMID: 33127568
No abstract available.
10.
Martinez-Mayorga K, Madariaga-Mazon A, Medina-Franco J, Maggiora G
Expert Opin Drug Discov
. 2020 Jan;
15(3):293-306.
PMID: 31965870
: Even though there have been substantial advances in our understanding of biological systems, research in drug discovery is only just now beginning to utilize this type of information. The...