Abigail R Dowling
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Explore the profile of Abigail R Dowling including associated specialties, affiliations and a list of published articles.
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10
Citations
158
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Recent Articles
1.
Obi A, Sharma S, Elfline M, Luke C, Dowling A, Cai Q, et al.
Sci Rep
. 2023 Feb;
13(1):3253.
PMID: 36828892
Deep venous thrombosis and residual thrombus burden correlates with circulating IL-6 levels in humans. To investigate the cellular source and role of IL-6 in thrombus resolution, Wild type C57BL/6J (WT),...
2.
Dowling A, Luke C, Cai Q, Pellerito A, Obi A, Henke P
JVS Vasc Sci
. 2022 Jun;
3:246-255.
PMID: 35647566
Objective: Deep vein thrombosis (DVT) and its sequela, post-thrombotic syndrome (PTS), remain a clinically significant problem. Interleukin-6 (IL-6) is a proinflammatory cytokine that is elevated in patients who develop PTS....
3.
Messinger D, Harris M, Cummings J, Thomas C, Yang T, Sweha S, et al.
Neuro Oncol
. 2022 May;
25(1):54-67.
PMID: 35605606
Background: Diffuse midline gliomas (DMG) are highly invasive brain tumors with rare survival beyond two years past diagnosis and limited understanding of the mechanism behind tumor invasion. Previous reports demonstrate...
4.
Kimball A, Tara Obi A, Luke C, Dowling A, Cai Q, Adili R, et al.
Thromb Haemost
. 2019 Dec;
120(2):289-299.
PMID: 31887775
Venous thrombosis (VT) resolution is a complex process, resembling sterile wound healing. Infiltrating blood-derived monocyte/macrophages (Mo/MΦs) are essential for the regulation of inflammation in tissue repair. These cells differentiate into...
5.
Qiu X, Dao H, Wang M, Heston A, Garcia K, Sangal A, et al.
PLoS One
. 2015 May;
10(5):e0121974.
PMID: 25946091
Reproduction requires adequate energy stores for parents and offspring to survive. Kiss1 neurons, which are essential for fertility, have the potential to serve as the central sensors of metabolic factors...
6.
Faulkner L, Dowling A, Stuart R, Nillni E, Hill J
Endocrinology
. 2015 Jan;
156(4):1372-85.
PMID: 25590244
Proopiomelanocortin (POMC)-derived peptides like α-melanocyte-stimulating hormone (MSH) substantially improve hepatic insulin sensitivity and regulate energy expenditure. Melanocortinergic agents are also powerful inducers of sexual arousal that are being investigated for...
7.
Kolli V, Stechschulte L, Dowling A, Rahman S, Czernik P, Lecka-Czernik B
PLoS One
. 2014 May;
9(5):e96323.
PMID: 24810249
Peroxisome proliferator activated receptor gamma (PPARγ) controls both glucose metabolism and an allocation of marrow mesenchymal stem cells (MSCs) toward osteoblast and adipocyte lineages. Its activity is determined by interaction...
8.
Genetic factors modulate the impact of pubertal androgen excess on insulin sensitivity and fertility
Dowling A, Nedorezov L, Qiu X, Marino J, Hill J
PLoS One
. 2013 Nov;
8(11):e79849.
PMID: 24278193
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive age women. The syndrome is caused by a combination of environmental influences and genetic predisposition. Despite extensive efforts,...
9.
Qiu X, Dowling A, Marino J, Faulkner L, Bryant B, Bruning J, et al.
Endocrinology
. 2013 Feb;
154(3):1337-48.
PMID: 23392256
Pubertal onset only occurs in a favorable, anabolic hormonal environment. The neuropeptide kisspeptin, encoded by the Kiss1 gene, modifies GnRH neuronal activity to initiate puberty and maintain fertility, but the...
10.
Marino J, Iler J, Dowling A, Chua S, Bruning J, Coppari R, et al.
PLoS One
. 2012 Nov;
7(10):e48643.
PMID: 23119079
Clinical research shows an association between polycystic ovary syndrome (PCOS) and chronic inflammation, a pathological state thought to contribute to insulin resistance. The underlying pathways, however, have not been defined....