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Abhishek Jauhari

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Articles 17
Citations 275
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Recent Articles
1.
Jauhari A, Monek A, Suofu Y, Amygdalos O, Singh T, Baranov S, et al.
J Pineal Res . 2025 Feb; 77(2):e70037. PMID: 39982401
Differentiation from neural progenitor to mature neuron requires a metabolic switch, whereby mature neurons become almost entirely dependent upon oxidative phosphorylation (OXPHOS) for ATP production. Although more efficient with respect...
2.
Yablonska S, Strohlein C, Baranov S, Yeh S, Patel A, Singh T, et al.
J Neurosci . 2025 Jan; 45(8). PMID: 39779371
Huntington's disease (HD), a neurodegenerative disease, affects approximately 30,000 people in the United States, with 200,000 more at risk. Mitochondrial dysfunction caused by mutant huntingtin (mHTT) drives early HD pathophysiology....
3.
Nowicki K, Mittal A, Hudson J, DAngelo M, McDowell M, Cao C, et al.
Transl Stroke Res . 2024 Nov; PMID: 39499487
Platelet aggregation is intimately associated with vascular inflammation and is commonly seen on routine histology studies of cerebral aneurysms. Platelets, when activated, have been shown to augment neutrophil response and...
4.
Yadav S, Jauhari A, Singh N, Pandey A, Sarkar S, Pandey S, et al.
Cell Mol Neurobiol . 2023 May; 43(7):3527-3553. PMID: 37219663
Parkinson's disease (PD) is a neurodegenerative disorder caused by the selective destruction of dopaminergic neurons (DA-nergic). Clinically, PD is diagnosed based on developing signs and symptoms. A neurological and physical...
5.
Suofu Y, Jauhari A, Nirmala E, Mullins W, Wang X, Li F, et al.
Neurosci Lett . 2022 Dec; 795:137043. PMID: 36586530
Microglial activation is readily detected following cerebral ischemia/reperfusion-induced injury. Activated microglia polarize into either classic pro-inflammatory M1 or protective M2 microglia following ischemia/reperfusion-induced injury. Melatonin is protective immediately after ischemia/reperfusion-induced...
6.
Jauhari A, Singh T, Yadav S
J Chem Neuroanat . 2022 Jan; 120:102072. PMID: 35063638
Controlled protein synthesis in different cell types is a prerequisite for the proper development and functioning of organs. Alterations in proteostasis either due to neurotoxicants (biological, chemical, or genetic) or...
7.
Baranov S, Jauhari A, Carlisle D, Friedlander R
Neurobiol Dis . 2021 Jul; 158:105451. PMID: 34298088
In healthy neurons, a mitochondrial membrane potential gradient exists whereby membrane potential is highest in the soma and decreases with distance from the nucleus. Correspondingly, distal mitochondria have more oxidative...
8.
Jauhari A, Baranov S, Suofu Y, Kim J, Singh T, Yablonska S, et al.
J Clin Invest . 2021 May; 131(9). PMID: 33938456
No abstract available.
9.
Jauhari A, Singh T, Mishra S, Shankar J, Yadav S
Toxicol Sci . 2020 May; 176(2):433-445. PMID: 32392329
Mitochondrial dysfunction is a common cause in pathophysiology of different neurodegenerative diseases. Elimination of dysfunctional and damaged mitochondria is a key requirement for maintaining homeostasis and bioenergetics of degenerating neurons....
10.
Jauhari A, Baranov S, Suofu Y, Kim J, Singh T, Yablonska S, et al.
J Clin Invest . 2020 Mar; 130(6):3124-3136. PMID: 32182222
Chronic inflammation is a pathologic feature of neurodegeneration and aging; however, the mechanism regulating this process is not understood. Melatonin, an endogenous free radical scavenger synthesized by neuronal mitochondria, decreases...