Abel Sousa
Overview
Explore the profile of Abel Sousa including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
246
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0
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Recent Articles
1.
Sousa A, Dugourd A, Memon D, Petursson B, Petsalaki E, Saez-Rodriguez J, et al.
Mol Syst Biol
. 2023 Jan;
19(3):e10631.
PMID: 36688815
Genetic alterations in cancer cells trigger oncogenic transformation, a process largely mediated by the dysregulation of kinase and transcription factor (TF) activities. While the mutational profiles of thousands of tumours...
2.
Gjerga E, Dugourd A, Tobalina L, Sousa A, Saez-Rodriguez J
J Proteome Res
. 2021 Mar;
20(4):2138-2144.
PMID: 33682416
Post-translational modifications of proteins play an important role in the regulation of cellular processes. The mass spectrometry analysis of proteome modifications offers huge potential for the study of how protein...
3.
Dugourd A, Kuppe C, Sciacovelli M, Gjerga E, Gabor A, Emdal K, et al.
Mol Syst Biol
. 2021 Jan;
17(1):e9730.
PMID: 33502086
Multi-omics datasets can provide molecular insights beyond the sum of individual omics. Various tools have been recently developed to integrate such datasets, but there are limited strategies to systematically extract...
4.
Sousa A, Ferreira M, Oliveira C, Ferreira P
Front Genet
. 2020 Aug;
11:808.
PMID: 32849808
Cancer has an important and considerable gender differential susceptibility confirmed by several epidemiological studies. Gastric (GC) and thyroid cancer (TC) are examples of malignancies with a higher incidence in males...
5.
Duenas M, Perez-Figueroa A, Oliveira C, Suarez-Cabrera C, Sousa A, Oliveira P, et al.
Sci Rep
. 2019 Jul;
9(1):10362.
PMID: 31316092
Non-muscle invasive bladder cancer (NMIBC) represents a crucial problem for the national health care systems due to its high rates of recurrence and the consequent need of frequent follow-ups. Here,...
6.
Sousa A, Goncalves E, Mirauta B, Ochoa D, Stegle O, Beltrao P
Mol Cell Proteomics
. 2019 Jun;
18(8 suppl 1):S114-S125.
PMID: 31239291
Proteogenomic studies of cancer samples have shown that copy-number variation can be attenuated at the protein level for a large fraction of the proteome, likely due to the degradation of...
7.
Bustos-Carpinteyro A, Oliveira C, Sousa A, Oliveira P, Pinheiro H, Carvalho J, et al.
BMC Cancer
. 2019 Jan;
19(1):69.
PMID: 30642281
Background: Diffuse gastric cancer (DGC) is associated with the reduction or absence of the expression of the cell adhesion protein E-cadherin (encoded by the CDH1 gene). Molecular characteristics are less...
8.
Ferreira P, Munoz-Aguirre M, Reverter F, Sa Godinho C, Sousa A, Amadoz A, et al.
Nat Commun
. 2018 Feb;
9(1):490.
PMID: 29440659
Post-mortem tissues samples are a key resource for investigating patterns of gene expression. However, the processes triggered by death and the post-mortem interval (PMI) can significantly alter physiologically normal RNA...