Abeer Fadda
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Explore the profile of Abeer Fadda including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
475
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0
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Recent Articles
1.
Shilbayeh S, Adeen I, Ghanem E, Aljurayb H, Aldilaijan K, AlDosari F, et al.
Front Pharmacol
. 2024 Feb;
15:1356763.
PMID: 38375040
Autism spectrum disorders (ASDs) encompass a broad range of phenotypes characterized by diverse neurological alterations. Genomic studies have revealed considerable overlap between the molecular mechanisms implicated in the etiology of...
2.
Hildebrand J, Lo B, Tomei S, Mattei V, Young S, Fitzgibbon C, et al.
Cell Death Dis
. 2021 Apr;
12(4):345.
PMID: 33795639
Maturity-onset diabetes of the young, MODY, is an autosomal dominant disease with incomplete penetrance. In a family with multiple generations of diabetes and several early onset diabetic siblings, we found...
3.
C2H2-Type Zinc Finger Proteins: Evolutionarily Old and New Partners of the Nuclear Hormone Receptors
Mackeh R, Marr A, Fadda A, Kino T
Nucl Recept Signal
. 2019 Feb;
15:1550762918801071.
PMID: 30718982
Nuclear hormone receptors (NRs) are evolutionarily conserved ligand-dependent transcription factors. They are essential for human life, mediating the actions of lipophilic molecules, such as steroid hormones and metabolites of fatty...
4.
Fadda A, El Anbari M, Ptitsyn A
BMC Med Genomics
. 2018 Mar;
11(Suppl 1):14.
PMID: 29504913
Background: Oscillations of different origin, period and amplitude play an important role in the regulation of cellular processes. Most widely studied is the circadian or approximately daily variation in gene...
5.
Fadda A, Syed N, Mackeh R, Papadopoulou A, Suzuki S, Jithesh P, et al.
Sci Rep
. 2017 Feb;
7:41598.
PMID: 28139699
The C2H2-type zinc finger protein ZNF764 acts as an enhancer for several steroid hormone receptors, and haploinsufficiency of this gene may be responsible for tissue resistance to multiple steroid hormones...
6.
Fadda A, Butt F, Tomei S, Deola S, Lo B, Robay A, et al.
BMC Med Genet
. 2016 Nov;
17(1):84.
PMID: 27855655
Background: Ligase IV syndrome, a hereditary disease associated with compromised DNA damage response mechanisms, and Urofacial syndrome, caused by an impairment of neural cell signaling, are both rare genetic disorders,...
7.
El Anbari M, Fadda A, Ptitsyn A
PLoS One
. 2015 Jul;
10(7):e0131111.
PMID: 26161537
Circadian oscillation in baseline gene expression plays an important role in the regulation of multiple cellular processes. Most of the knowledge of circadian gene expression is based on studies measuring...
8.
Fadda A, Ryten M, Droll D, Rojas F, Farber V, Haanstra J, et al.
Mol Microbiol
. 2014 Aug;
94(2):307-26.
PMID: 25145465
African trypanosomes are an excellent system for quantitative modelling of post-transcriptional mRNA control. Transcription is constitutive and polycistronic; individual mRNAs are excised by trans splicing and polyadenylation. We here measure...
9.
Erben E, Fadda A, Lueong S, Hoheisel J, Clayton C
PLoS Pathog
. 2014 Jun;
10(6):e1004178.
PMID: 24945722
In trypanosomatids, gene expression is regulated mainly by post-transcriptional mechanisms, which affect mRNA processing, translation and degradation. Currently, our understanding of factors that regulate either mRNA stability or translation is...
10.
Achcar F, Fadda A, Haanstra J, Kerkhoven E, Kim D, Leroux A, et al.
Adv Microb Physiol
. 2014 May;
64:115-43.
PMID: 24797926
The African trypanosome, Trypanosoma brucei, is a unicellular parasite causing African Trypanosomiasis (sleeping sickness in humans and nagana in animals). Due to some of its unique properties, it has emerged...