Abdolmohamad Rostami
Overview
Explore the profile of Abdolmohamad Rostami including associated specialties, affiliations and a list of published articles.
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146
Citations
4877
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Recent Articles
11.
SIRT1 inactivation switches reactive astrocytes to an antiinflammatory phenotype in CNS autoimmunity
Zhang W, Xiao D, Li X, Zhang Y, Rasouli J, Casella G, et al.
J Clin Invest
. 2022 Sep;
132(22).
PMID: 36136587
Astrocytes are highly heterogeneous in their phenotype and function, which contributes to CNS disease, repair, and aging; however, the molecular mechanism of their functional states remains largely unknown. Here, we...
12.
Rasouli J, Casella G, Zhang W, Xiao D, Kumar G, Fortina P, et al.
Front Immunol
. 2022 Jul;
13:912583.
PMID: 35860266
GM-CSF-producing T helper (Th) cells play a crucial role in the pathogenesis of autoimmune diseases such as multiple sclerosis (MS). Recent studies have identified a distinct population of GM-CSF-producing Th...
13.
Hwang D, Seyedsadr M, Watanabe Ishikawa L, Boehm A, Sahin Z, Casella G, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(14):e2111804119.
PMID: 35353625
The receptor for colony stimulating factor 1 (CSF-1R) is important for the survival and function of myeloid cells that mediate pathology during experimental autoimmune encephalomyelitis (EAE), an animal model of...
14.
Allahyari R, Heinsinger N, Hwang D, Jaffe D, Rasouli J, Shiers S, et al.
Cells
. 2022 Feb;
11(4).
PMID: 35203371
There is growing appreciation for astrocyte heterogeneity both across and within central nervous system (CNS) regions, as well as between intact and diseased states. Recent work identified multiple astrocyte subpopulations...
15.
Wu W, Tian J, Xiao D, Guo Y, Xiao Y, Wu X, et al.
Nanoscale
. 2022 Jan;
14(6):2393-2410.
PMID: 35088795
Targeted and effective drug delivery to central nervous system (CNS) lesions is a major challenge in the treatment of multiple sclerosis (MS). Extracellular vesicles (EVs) have great promise as a...
16.
Hwang D, Boehm A, Rostami A, Zhang G, Ciric B
J Neuroimmunol
. 2021 Nov;
362:577778.
PMID: 34814011
D-mannose (D-m) is a glucose epimer found in natural products, especially fruits. In mouse models of diabetes and airway inflammation, D-m supplementation via drinking water attenuated pathology by modifying cellular...
17.
Rostaminejad M, Rostami A, Behzad-Behbahani A, Dehbidi G, Kalantari T
Mol Biol Rep
. 2021 Nov;
49(2):1103-1111.
PMID: 34775574
Background: The kynurenine pathway (KP) can be involved in the pathogenesis of neurodegenerative diseases and excessive neurotoxic metabolite production. This study aimed to evaluate the effects of overexpression of murine...
18.
Munhoz J, Thome R, Rostami A, Watanabe Ishikawa L, Verinaud L, Raposo C
Peptides
. 2021 Sep;
146():170648.
PMID: 34537257
Peptides are molecules that have emerged as crucial candidates for the development of anticancer drugs. Spider venoms are a rich source of peptides (venom peptides - VPs) with biological effects....
19.
Rasouli J, Casella G, Ishikawa L, Thome R, Boehm A, Ertel A, et al.
Front Immunol
. 2021 Jun;
12:679498.
PMID: 34149716
IFN-β has been the treatment for multiple sclerosis (MS) for almost three decades, but understanding the mechanisms underlying its beneficial effects remains incomplete. We have shown that MS patients have...
20.
Xiao D, Zhang W, Wang Q, Li X, Zhang Y, Rasouli J, et al.
Mol Ther Methods Clin Dev
. 2021 Mar;
20:755-764.
PMID: 33738329
Inducible conditional knockout mice are important tools for studying gene function and disease therapy, but their generation is costly and time-consuming. We introduced clustered regularly interspaced short palindromic repeats (CRISPR)...