Abdol-Hossein Rezaeian
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Explore the profile of Abdol-Hossein Rezaeian including associated specialties, affiliations and a list of published articles.
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20
Citations
291
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Recent Articles
1.
Huang D, Rezaeian A, Wang J, Qi Y, Chen H, Inuzuka H, et al.
J Cancer Biol
. 2025 Feb;
5(2):44-60.
PMID: 40018367
Activating innate immune signaling in tumor cells to enhance anti-tumor immunity and increase T cell-mediated killing is the core objective of tumor immunotherapy. PRMT1, one of the most crucial PRMTs,...
2.
Huang D, Tu Z, Karnoub A, Wei W, Rezaeian A
Biomedicines
. 2024 Oct;
12(10).
PMID: 39457533
: Busulfan is an FDA-approved alkylating drug used in the chemotherapy of advanced acute myeloid leukemia. The precise mechanisms by which Busulfan kills spermatogonia stem cells (SSCs) are not yet...
3.
Rezaeian A, Wei W
Semin Cancer Biol
. 2024 Aug;
106-107:28-42.
PMID: 39197809
It is well documented that aging is associated with cancer, and likewise, cancer survivors display accelerated aging. As the number of aging individuals and cancer survivors continues to grow, it...
4.
Wang J, Huang D, Nguyen T, Phan L, Wei W, Rezaeian A
Biology (Basel)
. 2024 Jul;
13(7).
PMID: 39056676
Triple-negative breast cancer (TNBC) cells are often resistant to FAS (CD95)-mediated apoptosis, but the underlying molecular mechanism(s) is not fully understood yet. Notably, the expression of the type II transmembrane...
5.
Cetin M, Saatci O, Rezaeian A, Nageswara Rao C, Beneker C, Sreenivas K, et al.
Cell Chem Biol
. 2024 Jul;
31(11):1926-1941.e11.
PMID: 39043186
Lysyl oxidase (LOX) is upregulated in highly stiff aggressive tumors, correlating with metastasis, resistance, and worse survival; however, there are currently no potent, safe, and orally bioavailable small molecule LOX...
6.
Qi Y, Rezaeian A, Wang J, Huang D, Chen H, Inuzuka H, et al.
Biochim Biophys Acta Rev Cancer
. 2024 Jun;
1879(5):189140.
PMID: 38909632
FBXW7 is one of the most well-characterized F-box proteins, serving as substrate receptor subunit of SKP1-CUL1-F-box (SCF) E3 ligase complexes. SCF is responsible for the degradation of various oncogenic proteins...
7.
Dang F, Bai L, Dong J, Hu X, Wang J, Paulo J, et al.
Sci Transl Med
. 2023 Dec;
15(725):eadh7668.
PMID: 38055802
Targeting angiotensin-converting enzyme 2 (ACE2) represents a promising and effective approach to combat not only the COVID-19 pandemic but also potential future pandemics arising from coronaviruses that depend on ACE2...
8.
Rezaeian A, Dang F, Wei W
Neoplasia
. 2023 May;
41:100904.
PMID: 37148656
Circadian clock orchestrates the intergenic biochemical, physiological and behavioral changes to form an approximate 24h oscillation through the transcription-translation feedback loop (TTFL). Mechanistically, a heterodimer of transcriptional activator formed by...
9.
Rezaeian A, Inuzuka H, Wei W
Adv Protein Chem Struct Biol
. 2023 Apr;
135:179-201.
PMID: 37061331
The recent findings advance our knowledge for the prevention of the premature activation of the major oncogenic pathways including MYC and the cyclin D-cyclin-dependent kinases 4 and 6 (CDK4/6) axis....
10.
Rezaeian A, Phan L, Zhou X, Wei W, Inuzuka H
Neoplasia
. 2023 Mar;
38:100890.
PMID: 36871351
SKP2, an F-box protein of the SCF type of the E3 ubiquitin ligase complex, plays an important function in driving tumorigenesis through the destruction of numerous tumor-suppressive proteins. Besides its...