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Abby D Benninghoff

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Articles 54
Citations 779
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Recent Articles
1.
Odum A, Willis-Moore M, Callister K, Haynes J, Frye C, Scribner L, et al.
J Exp Anal Behav . 2025 Mar; PMID: 40085141
Tobacco use is the leading cause of death globally and in the United States. After decades of decline, driven by decreases in combusted tobacco use, nicotine product use has increased...
2.
Odum A, Willis-Moore M, Callister K, Haynes J, Frye C, Scribner L, et al.
bioRxiv . 2025 Jan; PMID: 39763771
Tobacco use is the leading cause of death globally and in the U.S. After decades of decline, driven by decreases in combusted tobacco use, nicotine product use has increased due...
3.
Heine L, Scarlett T, Wagner J, Lewandowski R, Benninghoff A, Tindle A, et al.
Inhal Toxicol . 2024 Mar; 36(2):106-123. PMID: 38477125
Objective: Occupational exposure to respirable crystalline silica (cSiO) has been linked to lupus development. Previous studies in young lupus-prone mice revealed that intranasal cSiO exposure triggered autoimmunity, preventable with docosahexaenoic...
4.
Anderson S, Dederich C, Elsberg J, Benninghoff A, Berreau L
ChemMedChem . 2024 Feb; 19(11):e202300682. PMID: 38369675
Carbon monoxide (CO) delivery molecules are of significant current interest as potential therapeutics, including for anticancer applications. A recent approach toward generating new types of materials-based anticancer agents involves combining...
5.
Chauhan P, Benninghoff A, Favor O, Wagner J, Lewandowski R, Rajasinghe L, et al.
Front Immunol . 2024 Feb; 15:1275265. PMID: 38361937
Introduction: Workplace exposure to respirable crystalline silica (cSiO) has been epidemiologically linked to lupus. Consistent with this, repeated subchronic intranasal cSiO instillation in lupus-prone NZBWF1 mice induces inflammation-/autoimmune-related gene expression,...
6.
Rodriguez D, Hintze K, Rompato G, Stewart E, Barton A, Mortensen-Curtis E, et al.
Nutrients . 2023 Mar; 15(6). PMID: 36986068
Consumption of the total Western diet (TWD) in mice has been shown to increase gut inflammation, promote colon tumorigenesis, and alter fecal microbiome composition when compared to mice fed a...
7.
Rodriguez D, Hintze K, Rompato G, Van Wettere A, Ward R, Phatak S, et al.
Nutrients . 2022 Dec; 14(24). PMID: 36558431
Black raspberries (BRB) are rich in anthocyanins with purported anti-inflammatory properties. However, it is not known whether dietary supplementation would ameliorate Western-diet enhanced gut inflammation and colon tumorigenesis. We employed...
8.
Heine L, Benninghoff A, Ross E, Rajasinghe L, Wagner J, Lewandowski R, et al.
Front Immunol . 2022 Nov; 13:972108. PMID: 36341330
Autoimmune diseases can be triggered by environmental toxicants such as crystalline silica dust (cSiO). Here, we characterized the dose-dependent immunomodulation and toxicity of the glucocorticoid (GC) prednisone in a preclinical...
9.
Lazarus L, Dederich C, Anderson S, Benninghoff A, Berreau L
ACS Med Chem Lett . 2022 Feb; 13(2):236-242. PMID: 35178180
Light-triggered carbon monoxide (CO) delivery molecules are of significant current interest for evaluating the role of CO in biology and as potential therapeutics. Herein we report the first example of...
10.
Rajasinghe L, Bates M, Benninghoff A, Wierenga K, Harkema J, Pestka J
Front Immunol . 2022 Feb; 12:781446. PMID: 35126352
Repeated short-term intranasal instillation of lupus-prone mice with crystalline silica (cSiO) induces inflammatory gene expression and ectopic lymphoid neogenesis in the lung, leading to early onset of systemic autoimmunity and...