Aaron Sievers
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Explore the profile of Aaron Sievers including associated specialties, affiliations and a list of published articles.
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10
Citations
69
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Recent Articles
1.
Hikmat W, Sievers A, Hausmann M, Hildenbrand G
Genes (Basel)
. 2024 Oct;
15(10).
PMID: 39457371
Background: It is widely accepted that the 3D chromatin organization in human cell nuclei is not random and recent investigations point towards an interactive relation of epigenetic functioning and chromatin...
2.
Henn L, Sievers A, Hausmann M, Hildenbrand G
Genes (Basel)
. 2024 Jan;
15(1).
PMID: 38254923
The specific characteristics of words (2 ≤ k ≤ 11) regarding genomic distribution and evolutionary conservation were recently found. Among them are, in high abundance, words with a tandem repeat...
3.
Sievers A, Sauer L, Bisch M, Sprengel J, Hausmann M, Hildenbrand G
Genes (Basel)
. 2023 Mar;
14(3).
PMID: 36981025
Dinucleotides are known as determinants for various structural and physiochemical properties of DNA and for binding affinities of proteins to DNA. These properties (e.g., stiffness) and bound proteins (e.g., transcription...
4.
Erenpreisa J, Giuliani A, Yoshikawa K, Falk M, Hildenbrand G, Salmina K, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769000
Complex functioning of the genome in the cell nucleus is controlled at different levels: (a) the DNA base sequence containing all relevant inherited information; (b) epigenetic pathways consisting of protein...
5.
Sievers A, Sauer L, Hausmann M, Hildenbrand G
Genes (Basel)
. 2021 Oct;
12(10).
PMID: 34680967
Several strongly conserved DNA sequence patterns in and between introns and intergenic regions (IIRs) consisting of short tandem repeats (STRs) with repeat lengths <3 bp have already been described in...
6.
Marbach F, Stoyanov G, Erger F, Stratakis C, Settas N, London E, et al.
Genet Med
. 2021 Apr;
23(8):1465-1473.
PMID: 33833410
Purpose: We characterize the clinical and molecular phenotypes of six unrelated individuals with intellectual disability and autism spectrum disorder who carry heterozygous missense variants of the PRKAR1B gene, which encodes...
7.
Hausmann M, Lee J, Sievers A, Krufczik M, Hildenbrand G
Methods Mol Biol
. 2020 Jul;
2175:65-77.
PMID: 32681484
During the last decade, genome sequence databases of many species have been more and more completed so that it has become possible to further develop a recently established technique of...
8.
Sievers A, Wenz F, Hausmann M, Hildenbrand G
Genes (Basel)
. 2018 Oct;
9(10).
PMID: 30287792
In this study, we pairwise-compared multiple genome regions, including genes, exons, coding DNA sequences (CDS), introns, and intergenic regions of 39 Animalia genomes, including Deuterostomia (27 species) and Protostomia (12...
9.
Krufczik M, Sievers A, Hausmann A, Lee J, Hildenbrand G, Schaufler W, et al.
Int J Mol Sci
. 2017 May;
18(5).
PMID: 28481278
Immunostaining and fluorescence in situ hybridization (FISH) are well established methods for specific labelling of chromatin in the cell nucleus. COMBO-FISH (combinatorial oligonucleotide fluorescence in situ hybridization) is a FISH...
10.
Sievers A, Bosiek K, Bisch M, Dreessen C, Riedel J, Fross P, et al.
Genes (Basel)
. 2017 Apr;
8(4).
PMID: 28422050
In genome analysis, -based comparison methods have become standard tools. However, even though they are able to deliver reliable results, other algorithms seem to work better in some cases. To...