Aaron Schetter
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Explore the profile of Aaron Schetter including associated specialties, affiliations and a list of published articles.
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10
Citations
845
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Recent Articles
1.
Li X, Pongor L, Tang W, Das S, Muys B, Jones M, et al.
Elife
. 2020 Oct;
9.
PMID: 33112233
Long noncoding RNAs (lncRNAs) are often associated with polysomes, indicating coding potential. However, only a handful of endogenous proteins encoded by putative lncRNAs have been identified and assigned a function....
2.
Jen E, Xu Q, Schetter A, Przepiorka D, Shen Y, Roscoe D, et al.
Clin Cancer Res
. 2018 Sep;
25(2):473-477.
PMID: 30254079
On March 29, 2018, the FDA granted accelerated approval for blinatumomab (Blincyto; Amgen, Inc.) for the treatment of adults and children with B-cell precursor acute lymphoblastic leukemia (BCP ALL) in...
3.
Li X, Subramanian M, Jones M, Chaudhary R, Singh D, Zong X, et al.
Cell Rep
. 2017 Sep;
20(10):2408-2423.
PMID: 28877474
Basal p53 levels are tightly suppressed under normal conditions. Disrupting this regulation results in elevated p53 levels to induce cell cycle arrest, apoptosis, and tumor suppression. Here, we report the...
4.
A Novel MIF Signaling Pathway Drives the Malignant Character of Pancreatic Cancer by Targeting NR3C2
Yang S, He P, Wang J, Schetter A, Tang W, Funamizu N, et al.
Cancer Res
. 2016 May;
76(13):3838-50.
PMID: 27197190
Pancreatic cancers with aberrant expression of macrophage migration inhibitory factor (MIF) are particularly aggressive. To identify key signaling pathways that drive disease aggressiveness in tumors with high MIF expression, we...
5.
Wallace T, Downey R, Seufert C, Schetter A, Dorsey T, Johnson C, et al.
Carcinogenesis
. 2014 May;
35(9):2074-83.
PMID: 24858205
Aberrant expression of subgroup k human endogenous retroviruses (HERV-K) has been observed in prostate cancer. This subgroup is unique because it encodes sequences in the human genome containing open reading...
6.
Olivo-Marston S, Hursting S, Perkins S, Schetter A, Khan M, Croce C, et al.
PLoS One
. 2014 Apr;
9(4):e94765.
PMID: 24732966
Obesity is an established colon cancer risk factor, while preventing or reversing obesity via a calorie restriction (CR) diet regimen decreases colon cancer risk. Unfortunately, the biological mechanisms underlying these...
7.
Funamizu N, Hu C, Lacy C, Schetter A, Zhang G, He P, et al.
Int J Cancer
. 2012 Jul;
132(4):785-94.
PMID: 22821831
MIF is a proinflammatory cytokine and is implicated in cancer. A higher MIF level is found in many human cancer and cancer-prone inflammatory diseases, including chronic pancreatitis and pancreatic cancer....
8.
Zhang G, Schetter A, He P, Funamizu N, Gaedcke J, Ghadimi B, et al.
PLoS One
. 2012 Feb;
7(2):e31507.
PMID: 22363658
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. To identify biologically relevant genes with prognostic and therapeutic significance in PDAC, we first performed the microarray gene-expression...
9.
Schetter A, Askjaer P, Piano F, Mattaj I, Kemphues K
Dev Biol
. 2005 Dec;
289(2):360-71.
PMID: 16325795
Nucleoporins are components of the nuclear pore, which is required for nucleo-cytoplasmic transport. We report a role for a subclass of nucleoporins in orienting the mitotic spindle in C. elegans...
10.
Cuenca A, Schetter A, Aceto D, Kemphues K, Seydoux G
Development
. 2003 Feb;
130(7):1255-65.
PMID: 12588843
Polarization of the C. elegans zygote along the anterior-posterior axis depends on cortically enriched (PAR) and cytoplasmic (MEX-5/6) proteins, which function together to localize determinants (e.g. PIE-1) in response to...