Aaron S Goldstein
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Explore the profile of Aaron S Goldstein including associated specialties, affiliations and a list of published articles.
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37
Citations
1129
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Recent Articles
1.
Gadalla D, Goldstein A
Ann Biomed Eng
. 2019 May;
48(3):1006-1015.
PMID: 31115719
Polycaprolactone (PCL) fiber scaffolds are attractive, albeit inert, substrates for ligament regeneration, that may be improved by incorporating trophic factors to guide tissue remodeling in vivo. In particular, immobilization of...
2.
Erndt-Marino J, Becerra-Bayona S, McMahon R, Goldstein A, Hahn M
J Biomed Mater Res A
. 2016 Apr;
104(9):2200-9.
PMID: 27101019
This work investigates the potential of cell layer-electrospun mesh constructs as coronary artery bypass grafts. These cell-mesh constructs were generated by first culturing a confluent layer of 10T½ smooth muscle...
3.
Thayer P, Verbridge S, Dahlgren L, Kakar S, Guelcher S, Goldstein A
J Biomed Mater Res A
. 2016 Apr;
104(8):1894-901.
PMID: 27037972
Electrospun microfibers are attractive for the engineering of oriented tissues because they present instructive topographic and mechanical cues to cells. However, high-density microfiber networks are too cell-impermeable for most tissue...
4.
Cardwell R, Kluge J, Thayer P, Guelcher S, Dahlgren L, Kaplan D, et al.
J Biomech Eng
. 2015 Apr;
137(7).
PMID: 25902471
Biomaterial substrates composed of semi-aligned electrospun fibers are attractive supports for the regeneration of connective tissues because the fibers are durable under cyclic tensile loads and can guide cell adhesion,...
5.
Samavedi S, Vaidya P, Gaddam P, Whittington A, Goldstein A
Biotechnol Bioeng
. 2014 Jun;
111(12):2549-59.
PMID: 24898875
Although bone-patellar tendon-bone (B-PT-B) autografts are the gold standard for repair of anterior cruciate ligament ruptures, they suffer from drawbacks such as donor site morbidity and limited supply. Engineered tissues...
6.
Thayer P, Dimling A, Plessl D, Hahn M, Guelcher S, Dahlgren L, et al.
Biomacromolecules
. 2013 Nov;
15(1):75-83.
PMID: 24266805
Electrospun meshes suffer from poor cell infiltration and limited thickness, which restrict their use to thin tissue applications. Herein, we demonstrate two complementary processes to overcome these limitations and achieve...
7.
Samavedi S, Whittington A, Goldstein A
Acta Biomater
. 2013 Jun;
9(9):8037-45.
PMID: 23791671
Calcium phosphate ceramics (CPCs) have been widely used as biomaterials for the regeneration of bone tissue because of their ability to induce osteoblastic differentiation in progenitor cells. Despite the progress...
8.
Cardwell R, Dahlgren L, Goldstein A
J Tissue Eng Regen Med
. 2012 Oct;
8(12):937-45.
PMID: 23038413
Efforts to develop engineered tendons and ligaments have focused on the use of a biomaterial scaffold and a stem cell source. However, the ideal scaffold microenvironment to promote stem cell...
9.
Samavedi S, Guelcher S, Goldstein A, Whittington A
Biomaterials
. 2012 Jul;
33(31):7727-35.
PMID: 22835644
Biomaterial scaffolds with gradients in architecture, mechanical and chemical properties have the potential to improve the osseointegration of ligament grafts by recapitulating phenotypic gradients that exist at the natural ligament-bone...
10.
Kavlock K, Whang K, Guelcher S, Goldstein A
J Biomater Sci Polym Ed
. 2012 Feb;
24(1):77-93.
PMID: 22304961
Segmented polyurethanes (PURs), consisting of degradable poly(a-hydroxy ester) soft segments and aminoacid-derived chain extenders, are biocompatible elastomers with tunable mechanical and degradative properties suitable for a variety of tissue-engineering applications....