Aaron R J Hutton
Overview
Explore the profile of Aaron R J Hutton including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
210
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Recent Articles
1.
Fandino O, Hutton A, Zhang C, Abbate M, Naser Y, Li Y, et al.
Eur J Pharm Biopharm
. 2024 Dec;
207:114603.
PMID: 39643092
Throughout history, psychedelic compounds have been used for religious, spiritual and recreational purposes. A plethora of studies have reported the use of psychedelic compounds in the treatment of various conditions,...
2.
Li L, Anjani Q, Hutton A, Li M, Sabri A, Vora L, et al.
Drug Deliv Transl Res
. 2024 Nov;
PMID: 39565514
Hydrogel-forming microneedle (MN) arrays are minimally-invasive devices that can penetrate the stratum corneum, the main barrier to topical drug application, without causing pain. However, drug delivery using hydrogel-forming MN arrays...
3.
Ripolin A, Volpe-Zanutto F, Sabri A, Dos Santos V, Figueroba S, Bezerra A, et al.
Int J Pharm
. 2024 Aug;
665:124642.
PMID: 39208953
As of 2023, more than 200 million people worldwide are living with osteoporosis. Oral bisphosphonates (BPs) are the primary treatment but can cause gastrointestinal (GI) side effects, reducing patient compliance....
4.
Apolinario A, Naser Y, Volpe-Zanutto F, Vora L, Sabri A, Li M, et al.
J Control Release
. 2024 Aug;
374:76-88.
PMID: 39111598
The retinoid fenretinide (FENR) is a promising compound for preventing breast cancer recurrence but faces challenges due to poor solubility and low bioavailability. This study explores the development of dissolving...
5.
Ghanma R, Anjani Q, Naser Y, Sabri A, Hutton A, Vora L, et al.
Eur J Pharm Biopharm
. 2024 Jul;
202:114415.
PMID: 39013492
Hydrogel-forming microneedle array patches (HFMAPs) are microneedles that create microconduits upon insertion and swelling in the skin, potentially allowing prolonged drug delivery without generating sharps waste. Delivering hydrophobic drugs using...
6.
Ghanma R, Naser Y, Anjani Q, Sabri A, Hutton A, Vora L, et al.
Int J Pharm
. 2024 Jun;
660:124342.
PMID: 38880253
Schizophrenia is a psychiatric disorder that results from abnormal levels of neurotransmitters in the brain. Risperidone (RIS) is a common drug prescribed for the treatment of schizophrenia. RIS is a...
7.
Zhang C, Wu Y, Hutton A, Sabri A, Hobson J, Savage A, et al.
Int J Pharm
. 2024 Jun;
660:124317.
PMID: 38851410
Human immunodeficiency virus (HIV) continues to pose a serious threat to global health. Oral preexposure prophylaxis (PrEP), considered highly effective for HIV prevention, is the utilisation of antiretroviral (ARV) drugs...
8.
McGuckin M, Hutton A, Davis E, Sabri A, Ripolin A, Himawan A, et al.
Mol Pharm
. 2024 Apr;
21(5):2512-2533.
PMID: 38602861
Parkinson's disease (PD) is a debilitating neurodegenerative disease primarily impacting neurons responsible for dopamine production within the brain. Pramipexole (PRA) is a dopamine agonist that is currently available in tablet...
9.
Demartis S, Rassu G, Anjani Q, Volpe-Zanutto F, Hutton A, Sabri A, et al.
J Control Release
. 2024 Mar;
369:363-375.
PMID: 38554770
The lymphatic system is active in several processes that regulate human diseases, among which cancer progression stands out. Thus, various drug delivery systems have been investigated to promote lymphatic drug...
10.
Abraham A, Anjani Q, Adhami M, Hutton A, Larraneta E, Donnelly R
J Mater Chem B
. 2024 Mar;
12(18):4375-4388.
PMID: 38477350
Hydrogel-forming microneedles (HF-MNs) are composed of unique cross-linked polymers that are devoid of the active pharmaceutical ingredient (API) within the microneedle array. Instead, the API is housed in a reservoir...