Aaron M Keller
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Explore the profile of Aaron M Keller including associated specialties, affiliations and a list of published articles.
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10
Citations
91
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Recent Articles
1.
Yan G, Pan M, Keller A, Santiago A, Lofgren M, Banerjee R, et al.
bioRxiv
. 2025 Jan;
PMID: 39829891
Significance Statement: MMAB is important for B -dependent propionate metabolism in bacteria. Our findings reveal that conformation-driven binding mechanism underlines the negative cooperativity of MMAB, as it favors the binding...
2.
Keller A, DeVore M, Stich D, Vu D, Causgrove T, Werner J
Anal Chem
. 2018 Apr;
90(10):6109-6115.
PMID: 29671313
Single-molecule fluorescence resonance energy transfer (smFRET) remains a widely utilized and powerful tool for quantifying heterogeneous interactions and conformational dynamics of biomolecules. However, traditional smFRET experiments either are limited to...
3.
Karan N, Keller A, Sampat S, Roslyak O, Arefin A, Hanson C, et al.
Chem Sci
. 2017 Nov;
6(4):2224-false.
PMID: 29163879
Hybrid semiconductor-metal nanoscale constructs are of both fundamental and practical interest. Semiconductor nanocrystals are active emitters of photons when stimulated optically, while the interaction of light with nanosized metal objects...
4.
DeVore M, Stich D, Keller A, Ghosh Y, Goodwin P, Phipps M, et al.
Proc SPIE Int Soc Opt Eng
. 2015 May;
9338.
PMID: 25932286
Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the...
5.
Keller A, Ghosh Y, DeVore M, Phipps M, Stewart M, Wilson B, et al.
Adv Funct Mater
. 2015 Mar;
24(30):4796-4803.
PMID: 25798080
While semiconductor quantum dots (QDs) have been used successfully in numerous single particle tracking (SPT) studies due to their high photoluminescence efficiency, photostability, and broad palette of emission colors, conventional...
6.
Chen P, Keller A, Joshi C, Martell D, Andoy N, Benitez J, et al.
Biochemistry
. 2013 Sep;
52(41):7170-83.
PMID: 24053279
Understanding how cells regulate and transport metal ions is an important goal in the field of bioinorganic chemistry, a frontier research area that resides at the interface of chemistry and...
7.
Keller A, Benitez J, Klarin D, Zhong L, Goldfogel M, Yang F, et al.
J Am Chem Soc
. 2012 May;
134(21):8934-43.
PMID: 22578168
As part of intracellular copper trafficking pathways, the human copper chaperone Hah1 delivers Cu(+) to the Wilson's Disease Protein (WDP) via weak and dynamic protein-protein interactions. WDP contains six homologous...
8.
Benitez J, Keller A, Huffman D, Yatsunyk L, Rosenzweig A, Chen P
Faraday Discuss
. 2011 Feb;
148:71-82.
PMID: 21322478
Metallochaperones undertake specific interactions with their target proteins to deliver metal ions inside cells. Understanding how these protein interactions are coupled with the underlying metal transfer process is important, but...
9.
Benitez J, Keller A, Chen P
Methods Enzymol
. 2010 Jun;
472:41-60.
PMID: 20580959
Protein-protein interactions are fundamental biological processes. While strong protein interactions are amenable to many characterization techniques including crystallography, weak protein interactions are challenging to study because of their dynamic nature....
10.
Chen P, Andoy N, Benitez J, Keller A, Panda D, Gao F
Nat Prod Rep
. 2010 May;
27(5):757-67.
PMID: 20442963
To maintain normal metal metabolism, organisms utilize dynamic cooperation of many biomacromolecules for regulating metal ion concentrations and bioavailability. How these biomacromolecules work together to achieve their functions is largely...