Aaron Bensimon
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Explore the profile of Aaron Bensimon including associated specialties, affiliations and a list of published articles.
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40
Citations
2969
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Recent Articles
1.
Cabin-Flaman A, Monnier A, Coffinier Y, Audinot J, Gibouin D, Wirtz T, et al.
F1000Res
. 2016 Jul;
5:1437.
PMID: 27429742
Dynamic secondary ion mass spectrometry ( D-SIMS) imaging of combed DNA - the combing, imaging by SIMS or CIS method - has been developed previously using a standard NanoSIMS 50...
2.
Kaykov A, Taillefumier T, Bensimon A, Nurse P
Sci Rep
. 2016 Jan;
6:19636.
PMID: 26781994
DNA combing allows the investigation of DNA replication on genomic single DNA molecules, but the lengths that can be analysed have been restricted to molecules of 200-500 kb. We have...
3.
Vasale J, Boyar F, Jocson M, Sulcova V, Chan P, Liaquat K, et al.
Neuromuscul Disord
. 2015 Oct;
25(12):945-51.
PMID: 26420234
We compare molecular combing to Southern blot in the analysis of the facioscapulohumeral muscular dystrophy type 1 locus (FSHD1) on chromosome 4q35-qter (chr 4q) in genomic DNA specimens sent to...
4.
Zillner K, Komatsu J, Filarsky K, Kalepu R, Bensimon A, Nemeth A
Epigenomics
. 2015 Jun;
7(3):363-78.
PMID: 26077426
Aim: The synthesis of rRNA is a key determinant of normal and malignant cell growth and subject to epigenetic regulation. Yet, the epigenomic features of rDNA arrays clustered in nucleolar...
5.
Cheeseman K, Ropars J, Renault P, Dupont J, Gouzy J, Branca A, et al.
Nat Commun
. 2014 Jan;
5:2876.
PMID: 24407037
While the extent and impact of horizontal transfers in prokaryotes are widely acknowledged, their importance to the eukaryotic kingdom is unclear and thought by many to be anecdotal. Here we...
6.
Mahiet C, Ergani A, Huot N, Alende N, Azough A, Salvaire F, et al.
J Virol
. 2012 Jun;
86(16):8592-601.
PMID: 22674981
Herpes simplex virus 1 (HSV-1) is a human pathogen that leads to recurrent facial-oral lesions. Its 152-kb genome is organized in two covalently linked segments, each composed of a unique...
7.
Cheeseman K, Rouleau E, Vannier A, Thomas A, Briaux A, Lefol C, et al.
Hum Mutat
. 2012 Apr;
33(6):998-1009.
PMID: 22473970
The BRCA1 and BRCA2 genes are involved in breast and ovarian cancer susceptibility. About 2 to 4% of breast cancer patients with positive family history, negative for point mutations, can...
8.
Nguyen K, Walrafen P, Bernard R, Attarian S, Chaix C, Vovan C, et al.
Ann Neurol
. 2011 Oct;
70(4):627-33.
PMID: 22028222
Objective: The genetic variation underlying facioscapulohumeral muscular dystrophy (FSHD), 1 of the most common hereditary neuromuscular disorders, is complex, and associated with the contraction of a repeat array (D4Z4) at...
9.
Cabin-Flaman A, Monnier A, Coffinier Y, Audinot J, Gibouin D, Wirtz T, et al.
Anal Chem
. 2011 Aug;
83(18):6940-7.
PMID: 21851091
Studies of replication, recombination, and rearrangements at the level of individual molecules of DNA are often limited by problems of resolution or of perturbations caused by the modifications that are...
10.
Ozeri-Galai E, Lebofsky R, Rahat A, Bester A, Bensimon A, Kerem B
Mol Cell
. 2011 Jul;
43(1):122-31.
PMID: 21726815
Perturbed DNA replication in early stages of cancer development induces chromosomal instability preferentially at fragile sites. However, the molecular basis for this instability is unknown. Here, we show that even...