Aaron Bell
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Explore the profile of Aaron Bell including associated specialties, affiliations and a list of published articles.
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71
Citations
1512
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Recent Articles
1.
Monga S, Lehrich B, Lehrich B, Delgado E, Delgado E, Yasaka T, et al.
Res Sq
. 2024 Dec;
PMID: 39711542
First-line immune checkpoint inhibitor (ICI) combinations show responses in subsets of hepatocellular carcinoma (HCC) patients. Nearly half of HCCs are Wnt-active with mutations in (encoding for β-catenin), , or ,...
2.
Lehrich B, Tao J, Liu S, Hirsch T, Yasaka T, Cao C, et al.
JHEP Rep
. 2024 Nov;
6(12):101186.
PMID: 39583094
Background & Aims: Patients with β-catenin (encoded by )-mutated hepatocellular carcinoma (HCC) demonstrate heterogenous responses to first-line immune checkpoint inhibitors (ICIs). Precision-medicine based treatments for this subclass are currently in...
3.
Gayden J, Hu S, Joseph P, Delgado E, Liu S, Bell A, et al.
Am J Pathol
. 2023 Feb;
193(5):558-566.
PMID: 36773785
Hepatic zonation is critical for most metabolic functions in liver. Wnt signaling plays an important role in establishing and maintaining liver zonation. Yet, the anatomic expression of Wnt signaling components,...
4.
Argemi J, Latasa M, Atkinson S, Blokhin I, Massey V, Gue J, et al.
Nat Commun
. 2023 Feb;
14(1):757.
PMID: 36765087
No abstract available.
5.
Hu S, Liu S, Bian Y, Poddar M, Singh S, Cao C, et al.
Cell Rep Med
. 2022 Oct;
3(10):100754.
PMID: 36220068
The conclusive identity of Wnts regulating liver zonation (LZ) and regeneration (LR) remains unclear despite an undisputed role of β-catenin. Using single-cell analysis, we identified a conserved Wnt2 and Wnt9b...
6.
Espeholt L, Agrawal S, Sonderby C, Kumar M, Heek J, Bromberg C, et al.
Nat Commun
. 2022 Sep;
13(1):5145.
PMID: 36050311
Existing weather forecasting models are based on physics and use supercomputers to evolve the atmosphere into the future. Better physics-based forecasts require improved atmospheric models, which can be difficult to...
7.
Hu S, Cao C, Poddar M, Delgado E, Singh S, Singh-Varma A, et al.
Hepatology
. 2022 Jul;
77(5):1593-1611.
PMID: 35862186
Background And Aims: Liver regeneration (LR) following partial hepatectomy (PH) occurs via activation of various signaling pathways. Disruption of a single pathway can be compensated by activation of another pathway...
8.
Hu S, Molina L, Tao J, Liu S, Hassan M, Singh S, et al.
Gastroenterology
. 2022 May;
163(2):449-465.
PMID: 35550144
Background & Aims: Intrahepatic cholangiocarcinoma (ICC) is a devastating liver cancer with extremely high intra- and inter-tumoral molecular heterogeneity, partly due to its diverse cellular origins. We investigated clinical relevance...
9.
Xie Y, Sun R, Gao L, Guan J, Wang J, Bell A, et al.
Hepatol Commun
. 2022 Jan;
6(5):1123-1139.
PMID: 34981658
The oxysterol receptor liver X receptor (LXR) is a nuclear receptor best known for its function in the regulation of lipid and cholesterol metabolism. LXRs, both the α and β...
10.
Arattu Thodika F, Nanjundappa M, Dassios T, Bell A, Greenough A
J Perinat Med
. 2021 Nov;
50(3):327-333.
PMID: 34847313
Objectives: Pulmonary hypertension (PH) is a complication of bronchopulmonary dysplasia (BPD) and associated with increased mortality and morbidity. Our aim was to identify, in infants with BPD, the effect of...