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Aaraby Yoheswaran Nielsen

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Recent Articles
1.
Ge L, Danielsen M, Nielsen A, Skavenborg M, Langkjaer N, Thisgaard H, et al.
Molecules . 2025 Jan; 30(2). PMID: 39860082
The overexpression of the epidermal growth factor receptor (EGFR) in certain types of prostate cancers and glioblastoma makes it a promising target for targeted radioligand therapy. In this context, pairing...
2.
Poole S, Aning O, McKee V, Catley T, Nielsen A, Thisgaard H, et al.
Nucleic Acids Res . 2025 Jan; 53(1. PMID: 39777469
Copper compounds with artificial metallo-nuclease (AMN) activity are mechanistically unique compared to established metallodrugs. Here, we describe the development of a new dinuclear copper AMN, Cu2-BPL-C6 (BPL-C6 = bis-1,10-phenanthroline-carbon-6), prepared...
3.
Traynor S, Terp M, Nielsen A, Guldberg P, Jakobsen M, Pedersen P, et al.
Cancer Lett . 2022 Oct; 552:215982. PMID: 36309209
DNA methyltransferase (DNMT) inhibitors are used for treatment of certain hematological malignancies and exert anti-cancer activity through diverse mechanisms, including reexpression of tumor suppressor genes and anti-viral responses triggered by...
4.
Dam J, Langkjaer N, Baun C, Olsen B, Nielsen A, Thisgaard H
Molecules . 2022 Oct; 27(20). PMID: 36296411
Background: The somatostatin receptors 1-5 are overexpressed on neuroendocrine neoplasms and, as such, represent a favorable target for molecular imaging. This study investigates the potential of [F]AlF-NOTA-[1-Nal]-Octreotide and compares it...
5.
Nielsen A, Gjerstorff M
Int J Mol Sci . 2016 Jun; 17(6). PMID: 27275820
Genomic instability is a hallmark of human cancer and an enabling factor for the genetic alterations that drive cancer development. The processes involved in genomic instability resemble those of meiosis,...