A W Stowers
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Explore the profile of A W Stowers including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
229
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Recent Articles
1.
Hisaeda H, Collins W, Saul A, Stowers A
Vaccine
. 2001 Dec;
20(5-6):763-70.
PMID: 11738740
Transmission-blocking vaccines against malaria parasites target molecules expressed by sexual stage parasites to elicit antibodies that prevent the infection of the mosquito vector. Pvs25 and Pvs28, expressed on the surface...
2.
Brady C, Shimp R, Miles A, Whitmore M, Stowers A
Protein Expr Purif
. 2001 Nov;
23(3):468-75.
PMID: 11722185
P30P2MSP1(19) is a recombinant subunit vaccine derived from merozoite surface protein 1 (MSP1) of Plasmodium falciparum, the causative agent of malaria. P30P2MSP1(19) consists of two universal T-cell epitopes fused to...
3.
Kedzierski L, Black C, Stowers A, Goschnick M, Kaslow D, Coppel R
Vaccine
. 2001 Sep;
19(32):4661-8.
PMID: 11535314
The gene encoding the Plasmodium yoelii homologue of P. falciparum merozoite surface proteins 4 (MSP4) and 5 (MSP5) has been expressed in Escherichia coli and Saccharomyces cerevisiae. The protein contains...
4.
Stowers A, MILLER L
Trends Parasitol
. 2001 Sep;
17(9):415-9.
PMID: 11530352
The development of malaria blood-stage vaccines is gathering momentum: there are several new funding initiatives, one multiantigen formulation is currently being tested and at least one other blood-stage vaccine is...
5.
Stowers A, Cioce V, Shimp R, Lawson M, Hui G, Muratova O, et al.
Infect Immun
. 2001 Feb;
69(3):1536-46.
PMID: 11179324
In an attempt to produce a more defined, clinical-grade version of a vaccine based on Plasmodium falciparum merozoite surface protein 1 (MSP1), we evaluated the efficacy of two recombinant forms...
6.
Stowers A, Zhang Y, Shimp R, Kaslow D
Yeast
. 2001 Feb;
18(2):137-50.
PMID: 11169756
A recombinant protein expression system based on Saccharomyces cerevisiae has been used to express malarial vaccine candidate antigens. The antigens so produced have been used in three Phase 1 clinical...
7.
Hisaeda H, Stowers A, Tsuboi T, Collins W, Sattabongkot J, Suwanabun N, et al.
Infect Immun
. 2000 Nov;
68(12):6618-23.
PMID: 11083773
Transmission-blocking vaccines are one strategy for controlling malaria, whereby sexual-stage parasites are inhibited from infecting mosquitoes by human antibodies. To evaluate whether the recently cloned Plasmodium vivax proteins Pvs25 and...
8.
Stowers A, Keister D, Muratova O, Kaslow D
Infect Immun
. 2000 Sep;
68(10):5530-8.
PMID: 10992450
Each of the four epidermal growth factor (EGF)-like domains of the Plasmodium falciparum sexual-stage antigen Pfs25 has been individually expressed as a yeast-secreted recombinant protein (yEGF1 through yEGF4). All four...
9.
Stowers A, Cooper J, Ehrhardt T, Saul A
Mol Biochem Parasitol
. 1996 Nov;
82(2):167-80.
PMID: 8946383
Mice immunised with a recombinant form of malarial antigen rhoptry-associated protein 2 (RAP2) produce antisera which recognise the native protein by indirect immunofluorescence and immunoblotting. Purified IgG components of the...
10.
Stowers A, Spring K, Saul A
Biotechnology (N Y)
. 1995 Dec;
13(13):1498-1503.
PMID: 9636309
An electrophoretic procedure based on isotachophoresis has been developed for protein purification on a preparative scale in the 10 to 500 mg range. The system is simple, uses well understood...