A W Stadnyk
Overview
Explore the profile of A W Stadnyk including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
359
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Recent Articles
1.
Jain U, Midgen C, Woodruff T, Schwaeble W, Stover C, Stadnyk A
Clin Exp Immunol
. 2017 Jan;
188(1):36-44.
PMID: 28052346
Intestinal mucositis is a serious complication of chemotherapy that leads to significant morbidity that may require dose or drug adjustments. Specific mitigating strategies for mucositis are unavailable, due partly to...
2.
Moore-Connors J, Kim H, Marshall J, Stadnyk A, Halperin S, Wang J
Mucosal Immunol
. 2014 Jun;
8(1):94-106.
PMID: 24938746
Regulatory B (Breg) cells are known to modulate immune responses through predominantly interleukin-10 (IL-10)-dependent mechanisms and can be hypothetically divided into innate and adaptive subsets based on the nature of...
3.
Jain U, Woodruff T, Stadnyk A
Br J Pharmacol
. 2012 Aug;
168(2):488-501.
PMID: 22924972
Background And Purpose: Anti-complement therapies have not been advanced for treating the inflammatory bowel diseases (IBDs) despite a growing body of evidence that blocking C5a protects against induced colitis in...
4.
Liu Z, Li H, Wu X, Yoo B, Yan S, Stadnyk A, et al.
Oncogene
. 2006 Jun;
25(59):7680-90.
PMID: 16799641
Detachment of normal epithelial cells from the extracellular matrix triggers apoptosis, a phenomenon called anoikis. Conversely, carcinoma cells tend to be relatively more anoikis-resistant than their normal counterparts, and this...
5.
Joseph R, Yazer E, Hanakawa Y, Stadnyk A
Apoptosis
. 2005 Oct;
10(6):1221-33.
PMID: 16215681
Recent data indicates that chronic inflammation of the intestine such as Crohn's or ulcerative colitis puts those individuals at heightened risk for colorectal adenocarcinoma. In this study, we examine the...
6.
Blake K, Carrigan S, Issekutz A, Stadnyk A
Clin Exp Immunol
. 2004 Apr;
136(2):262-8.
PMID: 15086389
Recruitment of polymorphonuclear leucocytes (PMN) across the intestinal epithelium is dependent on specific adhesion molecules and chemoattractants diffusing from the intestinal lumen. The present understanding is that in response to...
7.
Stadnyk A, DOLLARD C, Issekutz T, Issekutz A
Gut
. 2002 Apr;
50(5):629-35.
PMID: 11950807
Background: Neutrophils may exacerbate intestinal inflammatory diseases through secretion of proteolytic enzymes and reactive oxygen and nitrogen intermediates. Aims: To define the mechanisms involved in neutrophil infiltration into the non-steroidal...
8.
Endogenous IL-1 and type II IL-1 receptor expression modulate anoikis in intestinal epithelial cells
Waterhouse C, Joseph R, Stadnyk A
Exp Cell Res
. 2001 Aug;
269(1):109-16.
PMID: 11525644
We previously reported that IL-1beta and the decoy receptor for IL-1 (IL-1RII) are expressed by intestinal epithelial cells (IEC) during detachment-induced cell death, or "anoikis." We now investigated whether IL-1...
9.
Zhou J, Carr R, Liwski R, Stadnyk A, Lee T
J Immunol
. 2001 Jun;
167(1):107-13.
PMID: 11418638
We have previously reported that oral administration of allogeneic rat spleen cells before kidney allotransplantation significantly prolongs graft survival. This prolongation was alloantigen specific and was associated with a decrease...
10.
Waterhouse C, Joseph R, Winsor G, Lacombe T, Stadnyk A
J Interferon Cytokine Res
. 2001 May;
21(4):223-30.
PMID: 11359653
The intestinal epithelial cell (IEC) represents the first cellular barrier to infection. Consistent with this sentinel role, IEC are known to produce a variety of chemokines in response to bacterial...