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A Urumov

Explore the profile of A Urumov including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 28
Followers 0
Related Specialties
Chemistry
Pharmacology
Biochemistry
Top 10 Co-Authors
D Hupe
T Holler
C Nouhan
C Gajda
B D Tait
E A Lunney
E Zeikus
S E Hagen
S J Gracheck
G Zeikus
Published In
J Med Chem
Pharmazie
Bioorg Med Chem
Antibiotiki
Am J Physiol
Affiliations
Soon will be listed here.
Recent Articles
1.
4-Hydroxy-5,6-dihydropyrones as inhibitors of HIV protease: the effect of heterocyclic substituents at C-6 on antiviral potency and pharmacokinetic parameters
Hagen S, Domagala J, Gajda C, Lovdahl M, Tait B, Wise E, et al.
J Med Chem . 2001 Jun; 44(14):2319-32. PMID: 11428926
Due largely to the emergence of multi-drug-resistant HIV strains, the development of new HIV protease inhibitors remains a high priority for the pharmaceutical industry. Toward this end, we previously identified...
2.
5,6-Dihydropyran-2-ones possessing various sulfonyl functionalities: potent nonpeptidic inhibitors of HIV protease
Boyer F, Vara Prasad J, Domagala J, Ellsworth E, Gajda C, Hagen S, et al.
J Med Chem . 2000 Mar; 43(5):843-58. PMID: 10715152
On the basis of previous SAR findings and molecular modeling studies, a series of compounds were synthesized which possessed various sulfonyl moieties substituted at the 4-position of the C-3 phenyl...
3.
Nonpeptidic HIV protease inhibitors possessing excellent antiviral activities and therapeutic indices. PD 178390: a lead HIV protease inhibitor
Prasad J, Boyer F, Domagala J, Ellsworth E, Gajda C, Hamilton H, et al.
Bioorg Med Chem . 2000 Feb; 7(12):2775-800. PMID: 10658583
With the insight generated by the availability of X-ray crystal structures of various 5,6-dihydropyran-2-ones bound to HIV PR, inhibitors possessing various alkyl groups at the 6-position of 5,6-dihydropyran-2-one ring were...
4.
Molecular mechanisms for the growth factor action of gastrin
Todisco A, Takeuchi Y, Urumov A, Yamada J, Stepan V, Yamada T
Am J Physiol . 1997 Nov; 273(4):G891-8. PMID: 9357832
We have previously observed that gastrin has a cholecystokinin B (CCK-B) receptor-mediated growth-promoting effect on the AR42J rat pancreatic acinar cell line and that this effect is paralleled by induction...
5.
Comparative bioavailability studies of some oral amoxicillin products in rabbits
Kahr R, Urumov A, MINKOV E
Pharmazie . 1985 Oct; 40(10):734-5. PMID: 4080794
No abstract available.
6.
[Some changes in the antigenic complex of Bacillus anthracis under the action of streptomycin]
ZHELEVA M, Genova I, Urumov A
Antibiotiki . 1974 Aug; 19(8):729-32. PMID: 4375942
No abstract available.