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A Rissanen

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Articles 140
Citations 3460
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Recent Articles
1.
Kaartinen M, Arora M, Heinonen S, Hang A, Barry A, Lundbom J, et al.
Int J Obes (Lond) . 2020 Nov; 45(3):577-587. PMID: 33221826
Objective: F13A1/FXIII-A transglutaminase has been linked to adipogenesis in cells and to obesity in humans and mice, however, its role and associated molecular pathways in human acquired excess weight have...
2.
Jokinen R, Rinnankoski-Tuikka R, Kaye S, Saarinen L, Heinonen S, Myohanen M, et al.
Int J Obes (Lond) . 2017 Dec; 42(4):817-825. PMID: 29203860
Objectives: We investigated whether (1) subcutaneous adipose tissue (SAT) mitochondrial capacity predicts weight loss success and (2) weight loss ameliorates obesity-related SAT mitochondrial abnormalities. Methods: SAT biopsies were obtained from...
3.
Bollepalli S, Kaye S, Heinonen S, Kaprio J, Rissanen A, Virtanen K, et al.
Int J Obes (Lond) . 2017 Oct; 42(3):412-423. PMID: 28978976
Background: Few studies have examined both gene expression and DNA methylation profiles in subcutaneous adipose tissue (SAT) during long-term weight loss. Thus, molecular mechanisms in weight loss and regain remain...
4.
Berntzen B, Jukarainen S, Kataja M, Hakkarainen A, Lundbom J, Lundbom N, et al.
Scand J Med Sci Sports . 2017 Aug; 28(3):1048-1055. PMID: 28833625
This study aims to investigate (i) how monozygotic (MZ) twin pairs who are discordant for body mass index (BMI) differ for objectively and subjectively measured physical activity (PA) and cardiorespiratory...
5.
Muniandy M, Heinonen S, Yki-Jarvinen H, Hakkarainen A, Lundbom J, Lundbom N, et al.
Int J Obes (Lond) . 2017 Apr; 41(8):1176-1184. PMID: 28439093
Background: Subcutaneous adipose tissue (SAT) undergoes major changes in obesity, but little is known about the whole-genome scale patterns of these changes or about their variation between different obesity sub-groups....
6.
Jarvinen E, Ismail K, Muniandy M, Bogl L, Heinonen S, Tummers M, et al.
Int J Obes (Lond) . 2015 Nov; 40(5):788-95. PMID: 26601567
Background: Biotin acts as a coenzyme for carboxylases regulating lipid and amino-acid metabolism. We investigated alterations of the biotin-dependent functions in obesity and the downstream effects of biotin restriction in...
7.
Pietilainen K, Ismail K, Jarvinen E, Heinonen S, Tummers M, Bollepalli S, et al.
Int J Obes (Lond) . 2015 Oct; 40(4):654-61. PMID: 26499446
Background: Little is known about epigenetic alterations associated with subcutaneous adipose tissue (SAT) in obesity. Our aim was to study genome-wide DNA methylation and gene expression differences in SAT in...
8.
Visscher T, Heitmann B, Rissanen A, Lahti-Koski M, Lissner L
Int J Obes (Lond) . 2014 Jun; 39(2):189-98. PMID: 24909829
Recent epidemiologic papers are presenting prevalence data suggesting breaks and decreases in obesity rates. However, before concluding that the obesity epidemic is not increasing anymore, the validity of the presented...
9.
Heinonen S, Saarinen L, Naukkarinen J, Rodriguez A, Fruhbeck G, Hakkarainen A, et al.
Int J Obes (Lond) . 2014 Feb; 38(11):1423-31. PMID: 24549139
Background: Adipocyte size and number have been suggested to predict the development of metabolic complications in obesity. However, the genetic and environmental determinants behind this phenomenon remain unclear. Methods: We...
10.
Naukkarinen J, Heinonen S, Hakkarainen A, Lundbom J, Vuolteenaho K, Saarinen L, et al.
Diabetologia . 2013 Oct; 57(1):167-76. PMID: 24100782
Aims/hypothesis: Not all obese individuals display the metabolic disturbances commonly associated with excess fat accumulation. Mechanisms maintaining this 'metabolically healthy obesity' (MHO) are as yet unknown. We aimed to study...