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A R Kornblihtt

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Articles 49
Citations 1289
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Recent Articles
1.
Allo M, Schor I, Munoz M, de la Mata M, Agirre E, Valcarcel J, et al.
Cold Spring Harb Symp Quant Biol . 2011 Feb; 75:103-11. PMID: 21289049
Alternative splicing affects more than 90% of human genes. Coupling between transcription and splicing has become crucial in the complex network underlying alternative splicing regulation. Because chromatin is the real...
2.
Adrover M, Munoz M, Baez M, Thomas J, Kornblihtt A, Epstein A, et al.
Biochimie . 2010 Aug; 92(12):1839-46. PMID: 20709138
To block expression of NMDA receptor NR1 subunit, we injected into rat hippocampus a Herpes Simplex Virus type 1 derived vector bearing a sequence for NR1 antisense. RT-PCR assays with...
3.
Kadener S, Cramer P, Nogues G, Cazalla D, de la Mata M, Fededa J, et al.
EMBO J . 2001 Oct; 20(20):5759-68. PMID: 11598018
Here we investigate the promoter control of alternative splicing by studying two transcriptional activators on templates under replicating conditions. SV40 large T-antigen (T-Ag) activates template replication only 2-fold but transcription...
4.
Cramer P, Srebrow A, Kadener S, Werbajh S, de la Mata M, MELEN G, et al.
FEBS Lett . 2001 Jun; 498(2-3):179-82. PMID: 11412852
A large body of work has proved that transcription by RNA polymerase II and pre-mRNA processing are coordinated events within the cell nucleus. Capping, splicing and polyadenylation occur while transcription...
5.
Kornblihtt A
Medicina (B Aires) . 2001 May; 61(2):232-4. PMID: 11374149
No abstract available.
6.
Diaz Anel A, Rossi M, Espinosa J, Guida C, Freitas F, Kornblihtt A, et al.
J Eukaryot Microbiol . 2000 Dec; 47(6):555-60. PMID: 11128707
Differential display of mRNAs from Trypanosoma cruzi epimastigote and metacyclic trypomastigote stages showed several mRNA species differing in their expression level. The cDNA corresponding to one of these mRNAs was...
7.
Kornblihtt A
Medicina (B Aires) . 2000 Jun; 60(1):9-16. PMID: 10835695
This paper reviews basic concepts of modern molecular biology with the premise that its influence in today's medicine is so important that its knowledge cannot remain limited to a few...
8.
Iglesias D, Telleria D, Viribay M, Herrera M, Bernath V, Kornblihtt A, et al.
Nephrol Dial Transplant . 2000 Mar; 15(4):477-80. PMID: 10727541
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a genetically heterogeneous disorder that can be caused by mutations in at least three different genes. Several mutations have been identified in...
9.
Cramer P, Caceres J, Cazalla D, Kadener S, Muro A, Baralle F, et al.
Mol Cell . 1999 Sep; 4(2):251-8. PMID: 10488340
Alternative mRNA splicing of the fibronectin EDI exon is controlled by a purine-rich exonic splicing enhancer (ESE), postulated as a binding site for SR proteins. By using a transient expression...
10.
Pesce C, Nogues G, Alonso C, Baralle F, Kornblihtt A
FEBS Lett . 1999 Sep; 457(3):445-51. PMID: 10471826
The fibronectin promoter contains an ATF/cyclic AMP (cAMP) response element (CRE) site two helical turns upstream of a CCAAT site with which it interacts. We investigated the effects of mutating...