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A Polverino

Explore the profile of A Polverino including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 632
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Recent Articles
1.
Coxon A, Bready J, Kaufman S, Estrada J, Osgood T, Canon J, et al.
J Endocrinol Invest . 2011 Mar; 35(2):181-90. PMID: 21422803
Background: Medullary thyroid cancer (MTC) is frequently associated with mutations in the tyrosine kinase Ret and with increased expression of vascular endothelial growth factor (VEGF) and VEGF receptor 2 (VEGFR2)....
2.
Gilbreth M, Yang P, Wang D, Frost J, Polverino A, Cobb M, et al.
Proc Natl Acad Sci U S A . 1996 Nov; 93(24):13802-7. PMID: 8943016
The Shk1 protein kinase, a homolog of Saccharomyces cerevisiae Ste20 and mammalian p21Cdc42/Rac-activated kinases, is an essential component of a Ras- and Cdc42-dependent signaling cascade required for cell viability, normal...
3.
Polverino A, Frost J, Yang P, Hutchison M, Neiman A, Cobb M, et al.
J Biol Chem . 1995 Nov; 270(44):26067-70. PMID: 7592806
In the evolutionarily distant yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe, genetic evidence suggests that activation of pheromone-induced mitogen-activated protein kinase (MAPK) cascades involves the function of the p21cdc42/racl-activated protein kinases...
4.
MARCUS S, Polverino A, Chang E, Robbins D, Cobb M, Wigler M
Proc Natl Acad Sci U S A . 1995 Jun; 92(13):6180-4. PMID: 7597098
We describe a protein kinase, Shk1, from the fission yeast Schizosaccharomyces pombe, which is structurally related to the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases. We provide genetic evidence...
5.
White M, Nicolette C, Minden A, Polverino A, Van Aelst L, Karin M, et al.
Cell . 1995 Feb; 80(4):533-41. PMID: 7867061
We have developed a generalized approach, using two hybrid interactions, to isolate Ha-Ras effector loop mutations that separate the ability of Ha-Ras to interact with different downstream effectors. These mutations...
6.
MARCUS S, Polverino A, Barr M, Wigler M
Proc Natl Acad Sci U S A . 1994 Aug; 91(16):7762-6. PMID: 8052657
We present genetic evidence for complex formation of STE5 and the STE11, STE7, and FUS3 protein kinases, the pheromone-responsive mitogen-activated protein kinase module of Saccharomyces cerevisiae. Interaction between STE5 and...
7.
Van Aelst L, Barr M, MARCUS S, Polverino A, Wigler M
Proc Natl Acad Sci U S A . 1993 Jul; 90(13):6213-7. PMID: 8327501
We used a Saccharomyces cerevisiae genetic system to detect the physical interaction of RAS and RAF oncoproteins. We also observed interaction between RAS and byr2, a protein kinase implicated as...
8.
MARCUS S, Wigler M, Xu H, Ballester R, Kawamukai M, Polverino A
Ciba Found Symp . 1993 Jan; 176:53-61; discussion 61-6. PMID: 8299425
This paper reviews recent progress in understanding the function of RAS in three systems: the budding yeast (Saccharomyces cerevisiae), the fission yeast (Schizosaccharomyces pombe) and Xenopus laevis oocytes. One of...
9.
Bochner F, Graham G, Polverino A, Imhoff D, Tregenza R, Rolan P, et al.
Eur J Clin Pharmacol . 1987 Jan; 32(2):153-8. PMID: 3582479
The pharmacokinetics of salicyl phenolic glucuronide (SPG) and other salicylic acid (SA) metabolites were studied at three aspirin dosage regimens in eight patients with rheumatoid arthritis. Each patient received 1,...