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A Palotie

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Articles 160
Citations 3188
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Recent Articles
21.
Service S, Verweij K, Lahti J, Congdon E, Ekelund J, Hintsanen M, et al.
Transl Psychiatry . 2012 Jul; 2:e116. PMID: 22832960
Temperament has a strongly heritable component, yet multiple independent genome-wide studies have failed to identify significant genetic associations. We have assembled the largest sample to date of persons with genome-wide...
22.
Merjonen P, Keltikangas-Jarvinen L, Jokela M, Seppala I, Lyytikainen L, Pulkki-Raback L, et al.
Transl Psychiatry . 2012 Jul; 1:e11. PMID: 22832427
Hostility is a multidimensional personality trait with changing expression over the life course. We performed a genome-wide association study (GWAS) of the components of hostility in a population-based sample of...
23.
Polvi A, Siren A, Kallela M, Rantala H, Artto V, Sobel E, et al.
Neurology . 2012 Jan; 78(3):202-9. PMID: 22218271
Objectives: To describe clinical characteristics and to identify susceptibility loci for epilepsy and migraine in a Finnish family with a complex phenotype. Methods: Participating family members were interviewed and medical...
24.
Kemppinen A, Kaprio J, Palotie A, Saarela J
BMJ Open . 2011 Oct; 1(1):e000053. PMID: 22021740
Background Although recent genome-wide association studies have identified several genetic variants contributing to the complex aetiology of multiple sclerosis (MS), expression and functional studies are required to further understand its...
25.
de Moor M, Costa P, Terracciano A, Krueger R, de Geus E, Toshiko T, et al.
Mol Psychiatry . 2010 Dec; 17(3):337-49. PMID: 21173776
Personality can be thought of as a set of characteristics that influence people's thoughts, feelings and behavior across a variety of settings. Variation in personality is predictive of many outcomes...
26.
Tikka-Kleemola P, Artto V, Vepsalainen S, Sobel E, Raty S, Kaunisto M, et al.
Neurology . 2010 Apr; 74(15):1171-7. PMID: 20385888
Objective: To identify susceptibility loci for visual migraine aura in migraine families primarily affected with scintillating scotoma type of aura. Methods: We included Finnish migraine families with at least 2...
27.
Kettunen J, Perola M, Martin N, Cornes B, Wilson S, Montgomery G, et al.
Int J Obes (Lond) . 2009 Sep; 33(11):1235-42. PMID: 19721450
Objective: To identify common loci and potential genetic variants affecting body mass index (BMI, kg m(-2)) in study populations originating from Europe. Design: We combined genome-wide linkage scans of six...
28.
Tikka-Kleemola P, Kaunisto M, Hamalainen E, Todt U, Gobel H, Kaprio J, et al.
Cephalalgia . 2009 Jun; 29(11):1224-31. PMID: 19558538
The effect of endothelin-1 and its receptors EDNRA and EDNRB in migraine with aura (MA) susceptibility is not established yet. We studied the association between the MA end-diagnosis and three...
29.
Marjamaa A, Newton-Cheh C, Porthan K, Reunanen A, Lahermo P, Vaananen H, et al.
J Intern Med . 2008 Nov; 265(4):448-58. PMID: 19019189
Objectives: QT interval prolongation is associated with increased risk of sudden cardiac death at the population level. As 30-40% of the QT-interval variability is heritable, we tested the association of...
30.
Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, et al.
Mol Psychiatry . 2008 Mar; 14(9):865-73. PMID: 18317464
Disrupted in schizophrenia 1 (DISC1) has been associated with risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression, autism and Asperger syndrome, but apart from in the original translocation family,...