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A P MacGowan

Explore the profile of A P MacGowan including associated specialties, affiliations and a list of published articles. Areas
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Articles 189
Citations 2155
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Recent Articles
1.
Noel A, Attwood M, Bowker K, MacGowan A
Int J Antimicrob Agents . 2024 Aug; 64(4):107304. PMID: 39146998
Objectives: To define the in vitro pharmacodynamics of taniborbactam against Enterobacterales with CTXM-15, KPC, AmpC, and OXA-48 β-lactamases. Methods: An in vitro pharmacokinetic model was used to simulate serum concentrations...
2.
Hamilton F, Albur M, Noel A, MacGowan A
J Antimicrob Chemother . 2021 May; 76(9):2489-2491. PMID: 33993247
No abstract available.
3.
Noel A, Attwood M, Bowker K, MacGowan A
J Antimicrob Chemother . 2021 May; 76(7):1840-1844. PMID: 33975336
Background: Tetracyclines are widely used as oral therapy of MRSA infection, however, the pharmacodynamic underpinning is absent. Objectives: We employed an in vitro pharmacokinetic model to study the pharmacodynamics of...
4.
Noel A, Attwood M, Bowker K, MacGowan A
J Antimicrob Chemother . 2020 Dec; 76(3):667-670. PMID: 33294925
Background: The pharmacodynamics of omadacycline have been extensively studied against Gram-positive pathogens but less information is available for Gram-negative pathogens. We describe the pre-clinical pharmacodynamics of omadacycline against Escherichia coli...
5.
Noel A, Attwood M, Bowker K, MacGowan A
J Antimicrob Chemother . 2019 Dec; 75(3):772-773. PMID: 31848597
No abstract available.
6.
Sweeney E, Lovering A, Bowker K, MacGowan A, Nelson S
Lett Appl Microbiol . 2019 Feb; 68(4):294-302. PMID: 30770577
Chronic osteomyelitis is difficult to treat, with biofilm growth and the diffusion barrier to antibiotics presented by bone contributory factors. The aim of this study was to develop and evaluate...
7.
Chin T, MacGowan A, Jacobson S, Donati M
J Hosp Infect . 2014 Apr; 87(1):11-24. PMID: 24767811
Background: Healthcare workers (HCWs) have the potential for increased exposure to infectious disease resulting from the provision of patient care. Pregnancy can confer specific problems in some infections for the...
8.
Reynolds R, Hope R, Warner M, MacGowan A, Livermore D, Ellington M
J Antimicrob Chemother . 2013 Apr; 68(7):1693-4. PMID: 23557922
No abstract available.
9.
Bowker K, Garvey M, Noel A, Tomaselli S, MacGowan A
J Antimicrob Chemother . 2013 Jan; 68(5):1130-8. PMID: 23361641
Objectives: We aim to further define the impact of the mechanism of fluoroquinolone resistance and inoculum load on the pharmacodynamic effects of levofloxacin and moxifloxacin on Streptococcus pneumoniae. Methods: The...
10.
Reynolds R, Hope R, Warner M, MacGowan A, Livermore D, Ellington M
J Antimicrob Chemother . 2012 Aug; 67(12):2912-8. PMID: 22899805
Objectives: There have been several reports of upward creep in vancomycin MICs for Staphylococcus aureus [predominantly methicillin-resistant S. aureus (MRSA)] over recent years, but only in single centres or using...