A P Kuprat
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Explore the profile of A P Kuprat including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
66
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Recent Articles
1.
Asgharian B, Price O, Borojeni A, Kuprat A, Colby S, Singh R, et al.
J Aerosol Sci
. 2025 Mar;
185.
PMID: 40060110
Existing one-dimensional (1D) models of aerosol dosimetry often ignore mixing mechanisms of inhaled aerosols during their transport in the lung. This mixing or aerosol dispersion results from different physical mechanisms...
2.
Kuprat A, Feng Y, Corley R, Darquenne C
J Aerosol Sci
. 2024 Dec;
183.
PMID: 39678160
Determining the fate of inhaled aerosols in the respiratory system is essential in assessing the potential toxicity of inhaled airborne materials, responses to airborne pathogens, or in improving inhaled drug...
3.
Kuprat A, Price O, Asgharian B, Singh R, Colby S, Yugulis K, et al.
J Aerosol Sci
. 2023 Aug;
174.
PMID: 37637507
Assessing the toxicity of airborne particulate matter or the efficacy of inhaled drug depends upon accurate estimates of deposited fraction of inhaled materials. approaches can provide important insights into site-...
4.
Asgharian B, Price O, Borojeni A, Kuprat A, Colby S, Singh R, et al.
J Aerosol Sci
. 2022 Nov;
166.
PMID: 36405567
Predictive dosimetry models play an important role in assessing health effect of inhaled particulate matter and in optimizing delivery of inhaled pharmaceutical aerosols. In this study, the commonly used 1D...
5.
Kuprat A, Jalali M, Jan T, Corley R, Asgharian B, Price O, et al.
J Aerosol Sci
. 2021 May;
151.
PMID: 34024935
The development of predictive aerosol dosimetry models has been a major focus of environmental toxicology and pharmaceutical health research for decades. One-dimensional (1D) models successfully predict overall deposition averages but...
6.
Kabilan S, Suffield S, Recknagle K, Jacob R, Einstein D, Kuprat A, et al.
J Aerosol Sci
. 2020 Dec;
99:64-77.
PMID: 33311732
Three-dimensional computational fluid dynamics and Lagrangian particle deposition models were developed to compare the deposition of aerosolized spores in the respiratory airways of a human with that of the rabbit,...
7.
Carson J, Kuprat A, Jiao X, Del Pin F, Einstein D
Comput Cardiol
. 2019 Sep;
36:377-380.
PMID: 31527991
A critical challenge in biomechanical simulations is the spatial discretization of complex fluid-solid geometries created from imaging. This is especially important when dealing with Lagrangian interfaces, as there must be...
8.
Kuprat A, Kabilan S, Carson J, Corley R, Einstein D
J Comput Phys
. 2013 Dec;
244.
PMID: 24347680
In this study, we present a novel multiscale computational framework for efficiently linking multiple lower-dimensional models describing the distal lung mechanics to imaging-based 3D computational fluid dynamics (CFD) models of...
9.
Corley R, Minard K, Kabilan S, Einstein D, Kuprat A, Harkema J, et al.
Inhal Toxicol
. 2009 Jun;
21(6):512-8.
PMID: 19519151
The percentages of total airflows over the nasal respiratory and olfactory epithelium of female rabbits were calculated from computational fluid dynamics (CFD) simulations of steady-state inhalation. These airflow calculations, along...
10.
Demirel M, Kuprat A, George D, Rollett A
Phys Rev Lett
. 2003 Feb;
90(1):016106.
PMID: 12570632
We demonstrate the importance of anisotropic interface properties in microstructure evolution by comparing computed evolved microstructures to final experimental microstructures of 5170 grains in 19 thin aluminum foil samples. This...