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A N Kalehua

Explore the profile of A N Kalehua including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 319
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Recent Articles
1.
Kalehua A, Nagel J, Whelchel L, Gides J, Pyle R, Smith R, et al.
Exp Cell Res . 2004 Jun; 297(1):197-211. PMID: 15194436
Intrahippocamal injections of kainic acid (KA) significantly increase the expression of monocyte chemoattractant protein-1 (MCP-1) and macrophage inflammatory protein-2 (MIP-2) in the ipsilateral hippocampus at 2-4 h and 21-45 days...
2.
Kalehua A, Taub D, Baskar P, Hengemihle J, Munoz J, Trambadia M, et al.
Gerontology . 2000 Apr; 46(3):115-28. PMID: 10754368
Background: Age-related defects in the development of peripheral inflammatory responses have been observed in rodents and humans. Objective: We examined the effects of age on a centrally injected endotoxin-induced cytokine...
3.
Long J, Kalehua A, Muth N, Calhoun M, Jucker M, Hengemihle J, et al.
Neurobiol Aging . 1999 Jan; 19(5):497-503. PMID: 9880052
Recent evidence suggests neuroglia-mediated inflammatory mechanisms may stimulate neurodegenerative processes in mammalian brain during aging. To test the hypothesis that the number of microglia and astrocytes increase in the hippocampus...
4.
Long J, Kalehua A, Muth N, Hengemihle J, Jucker M, Calhoun M, et al.
J Neurosci Methods . 1998 Nov; 84(1-2):101-8. PMID: 9821640
Microglia are brain cells of considerable interest because of their role in CNS inflammatory responses and strong association with neuritic plaques in Alzheimer's disease (AD). In the present study, immunocytochemistry...
5.
Rowland N, Kalehua A, Li B, Streit W
Brain Res . 1993 Oct; 624(1-2):35-43. PMID: 8252414
The frontal cortices of rats which received either D,L- or D-fenfluramine (DFEN) for 4 days were examined 18 h to 2 weeks following treatment for changes in synaptosomal uptake of...
6.
Morioka T, Kalehua A, Streit W
J Comp Neurol . 1993 Jan; 327(1):123-32. PMID: 8432904
We have studied the microglial reaction that accompanies cortical infarction induced by middle cerebral artery occlusion (MCAO). Lectin histochemistry with the B4-isolectin from Griffonia simplicifolia as well as immunocytochemistry with...
7.
Streit W, Morioka T, Kalehua A
Neuroreport . 1992 Feb; 3(2):146-8. PMID: 1535800
Delayed neuronal death induced by transient forebrain ischemia in the rat hippocampus is preceded by a prominent microglial reaction which begins within minutes after the ischemic injury. In the present...
8.
Morioka T, Kalehua A, Streit W
Acta Neuropathol . 1992 Jan; 83(2):149-57. PMID: 1557947
We show a differential up-regulation of immunomolecules in the rat dorsal hippocampus accompanying neuronal cell death as a consequence of transient forebrain ischemia (four-vessel occlusion model). Using a panel of...
9.
Morioka T, Kalehua A, Streit W
J Cereb Blood Flow Metab . 1991 Nov; 11(6):966-73. PMID: 1719009
We have examined the distribution and time course of the microglial reaction in the rat dorsal hippocampus after 25-min transient forebrain ischemia (four-vessel occlusion model). Microglial cells were visualized in...