A Mode
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Explore the profile of A Mode including associated specialties, affiliations and a list of published articles.
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66
Citations
483
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Recent Articles
11.
Lahuna O, Fernandez L, Karlsson H, Maiter D, Lemaigre F, Rousseau G, et al.
Proc Natl Acad Sci U S A
. 1997 Nov;
94(23):12309-13.
PMID: 9356445
Growth hormone (GH) binding to its receptor modulates gene transcription by influencing the amount or activity of transcription factors. In the rat, GH exerts sexually dimorphic effects on liver gene...
12.
Westin S, Sonneveld E, van der Leede B, van der Saag P, Gustafsson J, Mode A
Mol Cell Endocrinol
. 1997 May;
129(2):169-79.
PMID: 9202400
Rats deficient in vitamin A express low levels of P4502C7 mRNA in the liver. Administration of all-trans retinoic acid (at-RA) or growth hormone (GH) to deficient animals only partially restored...
13.
Oinonen T, Mode A, Lobie P, Lindros K
Biochem Pharmacol
. 1996 May;
51(10):1379-87.
PMID: 8787555
The effect of hypophysectomy and subsequent infusion of growth hormone (GH) or injections of triiodothyronine (T3) on the acinar expression pattern of four homonally regulated P450 isozymes was studied to...
14.
Mode A, Tollet P, Wells T, Carmignac D, Clark R, Chen W, et al.
Endocrinology
. 1996 Feb;
137(2):447-54.
PMID: 8593788
Human GH (hGH) acts by dimerizing two hGH receptors that bind to different sites in hGH. G120RhGH, an analog mutated in the second binding site to prevent receptor dimerization, acts...
15.
Tollet P, Lahuna O, Ahlgren R, Mode A, Gustafsson J
Mol Endocrinol
. 1995 Dec;
9(12):1771-81.
PMID: 8614413
Expression of the rat CYP2C12 gene is liver specific and is induced by GH at the transcriptional level. In primary cultures of rat hepatocytes, GH inducibility of CYP2C12 and the...
16.
Ahlgren R, Norstedt G, Baumbach W, Mode A
Mol Cell Endocrinol
. 1995 Aug;
113(1):11-7.
PMID: 8674809
At least two classes of mRNA for the GH receptor (GHR) and GH binding protein (GH BP) with different 5' untranslated first exons exist in the rat. One such class,...
17.
Tollet P, Hamberg M, Gustafsson J, Mode A
J Biol Chem
. 1995 May;
270(21):12569-77.
PMID: 7759504
The expression of CYP2C12 is liver-specific and regulated at the transcriptional level by growth hormone (GH). In attempts to elucidate the nature of signaling molecules mediating the GH regulation of...
18.
Strom A, Westin S, Eguchi H, Gustafsson J, Mode A
J Biol Chem
. 1995 May;
270(19):11276-81.
PMID: 7744763
The HepG2-specific P450 2C factor motif (HPF1-motif) is conserved in many hepatic cytochrome P450 genes (CYP). Its functional importance for rabbit CYP2C genes has led to the proposal that the...
19.
Legraverend C, Eguchi H, Strom A, Lahuna O, Mode A, Tollet P, et al.
Biochemistry
. 1994 Aug;
33(33):9889-97.
PMID: 8060996
The rat CYP2C13 gene (2C13) encodes one of the constitutive male forms of cytochrome P-450 that are involved in steroid metabolism. In addition to being developmentally regulated, the expression of...
20.
Strom A, Eguchi H, Mode A, Legraverend C, Tollet P, Stromstedt P, et al.
DNA Cell Biol
. 1994 Aug;
13(8):805-19.
PMID: 8068205
The cytochrome P450 gene CYP2C11, expressed in the liver of male rats, is transcriptionally regulated in a dual fashion by the sexually dimorphic secretion pattern of growth hormone. To enable...