A Mestek
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Explore the profile of A Mestek including associated specialties, affiliations and a list of published articles.
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10
Citations
459
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Recent Articles
1.
Tian M, Broxmeyer H, Fan Y, Lai Z, Zhang S, Aronica S, et al.
J Exp Med
. 1997 Apr;
185(8):1517-22.
PMID: 9126934
The mu opioid receptor is thought to be the cellular target of opioid narcotics such as morphine and heroin, mediating their effects in both pain relief and euphoria. Its involvement...
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3.
Liang Y, Mestek A, Yu L, CARR L
Brain Res
. 1995 May;
679(1):82-8.
PMID: 7648268
Opioid compounds have potent analgesic and euphoric properties. They act with specific cell-membrane receptors which have been pharmacologically defined into three major classes, mu, kappa and delta. These receptors are...
4.
Mestek A, Hurley J, Bye L, Campbell A, Chen Y, Tian M, et al.
J Neurosci
. 1995 Mar;
15(3 Pt 2):2396-406.
PMID: 7891175
Opioids are some of the most efficacious analgesics used in humans. Prolonged administration of opioids, however, often causes the development of drug tolerance, thus limiting their effectiveness. To explore the...
5.
Raynor K, Kong H, Mestek A, Bye L, Tian M, Liu J, et al.
J Pharmacol Exp Ther
. 1995 Jan;
272(1):423-8.
PMID: 7815359
Opioid drugs exert a wide spectrum of physiological and behavioral effects, including effects on pain perception, mood, motor control and autonomic functions. The effects of opioids are mediated via a...
6.
Delfs J, Kong H, Mestek A, Chen Y, Yu L, Reisine T, et al.
J Comp Neurol
. 1994 Jul;
345(1):46-68.
PMID: 8089277
The mu (mu) opioid receptors, which mediate the effects of morphine, are widely distributed in brain. We have examined the distribution of mRNA encoding a mu opioid receptor in rat...
7.
Chen Y, Fan Y, Liu J, Mestek A, Tian M, Kozak C, et al.
FEBS Lett
. 1994 Jun;
347(2-3):279-83.
PMID: 8034018
A cDNA was isolated from rat brain by low stringency hybridization with the rat mu opioid receptor cDNA. Sequence analysis of this clone indicated that it contains an open reading...
8.
Chen Y, Mestek A, Liu J, Yu L
Biochem J
. 1993 Nov;
295 ( Pt 3):625-8.
PMID: 8240267
By screening a rat brain cDNA library using a cloned mu opioid receptor cDNA as probe, a clone was identified that is very similar to both the mu and delta...
9.
Chen Y, Mestek A, Liu J, Hurley J, Yu L
Mol Pharmacol
. 1993 Jul;
44(1):8-12.
PMID: 8393525
Opioid drugs act on specific receptors to modulate a wide range of physiological functions. There are at least three types of opioid receptors, mu, delta, and kappa. Using a cDNA...
10.
Mestek A, Stauffer J, Tolan D
Nucleic Acids Res
. 1987 Dec;
15(24):10595.
PMID: 3697100
No abstract available.